Photodynamic Therapy with Pyoktanin Blue and Diode Laser for Elimination of <i>Enterococcus faecalis</i>

Masuda, Yoshiko; Sakagami, Hiroshi; Horiike, Masashi; Kadokura, Hiroshi; Yamasaki, Takahide; Klokkevold, Perry R.; Takei, Henry H.; Yokose, Satoshi

doi:10.21873/invivo.11298

Cited by 16 publications

(18 citation statements)

References 25 publications

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“…Em seguida, como medida para aumentar a eficácia da desinfecção foi empregado o azul de metileno 0,010% (Chimiolux) preenchendo toda a janela óssea e associando ao laser infravermelho de baixa potência, atuando assim como terapia fotodinâmica gerando a liberação de radicais livres que proporcionam efeito bactericida (Souza et al, 2019). A utilização do laser de baixa frequência é segura, de fácil manipulação e aceitação pelo paciente, técnica seletiva além de promover atividade antimicrobiana quando associado a um corante fotossensibilizador, não causa efeitos sistêmicos e não promove resistência bacteriana (Trindade et al, 2017;Souza et al, 2019;Vieira et al, 2018;Masuda et al, 2018). Após análise molecular sobre o efeito antimicrobiano da PDT que quando esta terapia é usada junto às cirurgias endodônticas, o nível de bactérias e estreptococos, presente na cavidade radicular e na superfície de corte, diminuiu significativamente.…”

Section: Discussionunclassified

Cirurgia parendodontica associada a terapia fotodinâmica: relato de caso com acompanhamento de 4 anos

Laranjeira

Silva

Vieira

et al. 2021

RSD

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A cirurgia parendodôntica constitui um conjunto de procedimentos que têm como objetivo reparar complicações que não puderam ser solucionados através da endodontia convencional, ou quando essa não é passível de execução. Este estudo teve como objetivo descrever o caso clínico de uma cirurgia parendodôntica associada a terapia fotodinâmica no elemento dental 11. O caso foi conduzido realizando o acesso ao sistema de canais radiculares de forma retrograda. Foram realizadas: antissepsia intra/ extra bucal, anestesia infiltrativa, retalho para acesso, confecção da loja óssea, apicectomia, retroinstrumentação, terapia fotodinâmica, retrobturação, preenchimento da loja óssea, reposicionamento do retalho e sutura com acompanhamento tomográfico de feixe cônico de 4 anos. Concluímos que, a associação do ato cirúrgico com a aplicação de laser de baixa potência através da terapia fotodinâmica potencializou a desinfecção e a eliminação de bactérias persistentes ao fracasso do tratamento endodôntico anterior, propiciando benefícios adicionais ao paciente quando comparado à técnicas cirúrgicas convencionais.

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Section: Discussionunclassified

Cirurgia parendodontica associada a terapia fotodinâmica: relato de caso com acompanhamento de 4 anos

Laranjeira

Silva

Vieira

et al. 2021

RSD

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“…Estrela, Estrela, Pécora et al (2003) [17], in their study evaluating the needed time for Ca(OH) 2 to eliminate S. aureus, E.faecalis, P. aeruginosa, B. subtilis, C. albicans, concluded that Ca(OH)2 paste was able to eliminate these microorganisms only after 60 days, and the same period for canal infected by a mix of the same microorganisms. The paste of Ca(OH) 2 said to be ineffective as intracanal medication over specific types of microorganisms [6,7], which may necessitate the use of reliable techniques that collaborate in the success of RCT [12].…”

Section: Discussionmentioning

confidence: 99%

“…The aPDT demonstrated antimicrobial effects in various studies using different wavelengths of the low power laser or LEDs, since specific and high absorption by a non-toxic photoactive dye, called a photosensitizer in the presence of oxygen promoting the photochemical reaction and production of reactive oxygen specimens (ROS) like hydroxyl, superoxide anion, Triplet Oxygen and Singlet Oxygen [10], which contributes to microorganisms disinfection. This procedure is a complementary technique beside irrigating solutions or intracanal medications [11,12], as well as being compatible and without thermal side effects over the surrounding tissue [12,13].…”

Section: Introductionmentioning

confidence: 99%

Endodontic treatment of a large periapical cyst with the aid of antimicrobial photodynamic therapy - Case report

Hasna

Ferrari

Carvalho

2019

BDS

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Introduction: Periapical cysts, especially those of great extension, represent a challenge for endodontics, since they are not repaired with traditional treatment. The aim of this case report was to evaluate the effectivity of antimicrobial photodynamic therapy “aPDT” when associated with calcium hydroxide Ca(OH)2 in treating such cysts. Case report: A 40-year-old female patient complained of bulging in the upper anterior region of the mouth. The clinical examination showed an extensive swollen periodontal area, painful with digital palpation, with a negative response to thermal tests on teeth 11 and 21. After traditional treatment, the canals of 11 and 21 were filled with photosensitizer methylene blue 0.005% pre irradiation time (PIT) of 5 minutes and irradiation by low power diode laser with visible red wavelength (660 nm) during 2 minutes without intervals, using an optical fiber delivering system with a helical movement from apical to cervical. Then the canal were filled with Ca(OH)2 paste for 45 days being changed each 15 days, and repeating the radiation. Results: After 45 days, the patient already had a bulging remission, with painless resistance to apical pressure in the region and signs of bone repair at the radiographic examination, and total absence of signs or symptoms. Conclusion: the association of aPDT with Ca(OH)2 paste is effective in treating of periapical lesions of great extension and avoid surgical treatment.Keywords: Antimicrobial; Calcium hydroxide; Diode Laser; Periapical cysts; Photodynamic Therapy; Root canal treatment.

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“…During PDT, PS influences the degree of damage. The previous report has shown that diode laser along with Pyoktanin was effective in eradiation of E. faecalis without having any toxicity to human dermal fibroblasts [38].…”

Section: Comparative Studiesmentioning

confidence: 96%

Using Photodynamic Therapy in Root Canal System – A Literature Review

Ajitha

2021

Innovare J H Sci

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Microorganisms do play in pulpal and periapical infection. Success of endodontic treatment aims at effective eradication of bacteria from the root canal space. This, in turn, prevents further microbial recolonization. Persistent microbial colonies in the root canal lead to failure of the endodontic treatment. With the advent of photodynamic therapy (PDT), a novel invasive approach is aimed at complete disinfection of root canal with elimination of bacteria. Therefore, this paper aims to highlight the efficiency of PDT in endodontics by reviewing the literature published in journals

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Photodynamic Therapy with Pyoktanin Blue and Diode Laser for Elimination of Enterococcus faecalis

Abstract: Abstract. Background

Cited by 16 publications

References 25 publications

Cirurgia parendodontica associada a terapia fotodinâmica: relato de caso com acompanhamento de 4 anos

Cirurgia parendodontica associada a terapia fotodinâmica: relato de caso com acompanhamento de 4 anos

Endodontic treatment of a large periapical cyst with the aid of antimicrobial photodynamic therapy - Case report

Using Photodynamic Therapy in Root Canal System – A Literature Review

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