Photodynamic therapy for the treatment of morphoea

Batchelor, R. J.

doi:10.1111/j.1365-2230.2008.02873.x

Cited by 26 publications

(12 citation statements)

References 7 publications

(7 reference statements)

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“…In four of the patients there was clinical improvement as determined by skin scoring, although only one of these patients showed histologic evidence of improvement. The side effects patients reported included burning sensation, dryness, erythema, pigmentation, and pruritus [61]. Table 1 lists an additional study.…”

Section: Clinical Evidence Of Phototherapy’s Efficacymentioning

confidence: 99%

Phototherapy in Scleroderma

Hassani

Feldman

2016

Dermatol Ther (Heidelb)

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Systemic and localized scleroderma are difficult to manage diseases with no accepted gold standard of therapy to date. Phototherapeutic modalities for scleroderma show promise. A PubMed search of information on phototherapy for scleroderma was conducted. The information was classified into effects on pathogenesis and clinical outcomes. Studies on photopheresis were excluded. There were no randomized, double-blind, placebo-controlled studies, and only three controlled studies. The vast majority of identified studies evaluated ultraviolet A1 (UVA1) phototherapy. More rigorous studies are needed to evaluate phototherapy in the treatment of scleroderma. Based on the limited studies available, 20–50 J/cm2 of UVA1 therapy 3–4 times a week for 30 treatments is recommended.

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Section: Clinical Evidence Of Phototherapy’s Efficacymentioning

confidence: 99%

Phototherapy in Scleroderma

Hassani

Feldman

2016

Dermatol Ther (Heidelb)

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“…[1] Seven subjects were enrolled and six subjects completed all treatments. After 6 weeks of weekly PDT treatments, no significant change was noted between treated and untreated lesions.…”

Section: Batchelormentioning

confidence: 99%

“…After 6 weeks of weekly PDT treatments, no significant change was noted between treated and untreated lesions. [1] This suggests that PDT is not an effective therapy for an active plaque morphea.…”

Section: Batchelormentioning

confidence: 99%

Morphea: Evidence-based recommendations for treatment

Fett¹

2012

Indian J Dermatol Venereol Leprol

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Morphea is a rare fibrosing disorder of the skin. Evidence-based treatment strategies in morphea are lacking. This review summarizes the available data on morphea treatment and provides therapeutic strategies based on morphea subtypes. The Cochrane Library, Medline and Embase from inception until May of 2011 were searched using the key words "morphea" and "morphea treatment." Reference lists of the resultant articles, as well as relevant reviews, were also searched. This review focuses on randomized controlled trials, prospective interventional trials without controls and retrospective reviews with greater than five subjects.

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“…The patient was offered either psoralen ultraviolet A (PUVA) photochemotherapy or UVA‐1 phototherapy at this point, but she declined these owing to time commitments and practical difficulties accessing the hospital. A literature review at this stage revealed two prospective trials that had previously shown some improvement in conventional morphoea after treatment with photodynamic therapy (PDT), and the patient was offered PDT on this basis.…”

mentioning

confidence: 99%