Photodynamic inactivation of human dental biofilm Isolated Streptococcus Mutans With 2 Photosensitizers - an In Vitro Study

Abstract

RESULTS:The control samples in dark showed a minor antimicrobial effect. Samples of bacterial suspension + PS + light irradiation expressed a pronounced antibacterial effect on Streptococcus mutans with small differences in the 2 tested PSs. CONCLUSIONS:The clinical strain Streptococcus mutans was susceptible to photodynamic inactivation by the two used photosensitizers: FotoSan® medium and ZnPcMe. Dark toxicity is to be neglected. ZnPcMe should undergo further trials and given the positive photodynamic effect in vitro, to be licensed for clinical use. FotoSan®medium should undergo further in vivo and in vitro experiments in order to establish an alternative protocol for caries prevention.