Photocrosslinkable Polymers for Biomedical Applications

Ferreira, Paula; Coelho, Jorge F. J.; Almeida, Joana; Gil, M.H.

doi:10.5772/18752

Cited by 20 publications

(22 citation statements)

References 68 publications

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“…In addition, they can be used as delivery frameworks that would be further engineered for delayed, localized release of medications, such as pain treatment drugs, antibiotics or chemotherapy. We can use them as mediums for growth factors [1][2][3][4][5] and actual cell lines for…”

Section: Introductionmentioning

confidence: 99%

RETRACTED: A Bio Polymeric Adhesive Produced by Photo Cross-Linkable Technique

2016

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Abstract:The advantages of photo polymerization methods compared to thermal techniques are: rapid cure reactions, low energy demands, solvent free requirements and room temperature use. In order to form a macromer, polycaprolactone (PCL) was cross-linked via ultraviolet power with 2-isocyanatoethyl methacrylate. Different methods of characterization were carried out: estimation of swelling capacity, adhesive capacity (using aminated substrates), surface energy (by contact angle), and attenuated total reflectance Fourier transform infrared. In addition to these experiments, we carried out dynamical mechanical thermal analysis, thermogravimetry and thermorphology characterizations of PCL. Thus, it has been concluded that the prepared macromer could be transformed into membranes that were effective as a medical adhesive. The degree of cross linking has been estimated using two different techniques: swelling of the samples and photo cross linking of the samples with different periods of irradiation at relatively high UV-power (600 mW/cm 2 ).

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Section: Introductionmentioning

confidence: 99%

RETRACTED: A Bio Polymeric Adhesive Produced by Photo Cross-Linkable Technique

2016

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“…The photocrosslinking technology through ultraviolet (UV) or visible light has been extensively used in several biomedical applications [1,3]. Recently, this technique has been focusing on the preparation of biomaterials with applications in important areas such as tissue engineering [5], biosensors [6], development of drug delivery systems [7], dental restorations in situ [8], surface modifications to control cell adhesion at the surface of different biomaterials [9,10] and bioadhesives [11].…”

Section: Introductionmentioning

confidence: 99%

“…The application of photopolymerization techniques in materials production has shown to provide a number of economic advantages over the usual thermal techniques, such as: rapid cure reaction even at room temperature, low energy requirements, use of solvent free formulations as well as low cost [1][2][3]. This methodology relies on light beams to start the photochemical reactions in organic materials (monomers, oligomers, polymers) in order to form a new polymeric system.…”

Section: Introductionmentioning

confidence: 99%

Synthesis, functionalization and characterization of UV-curable lactic acid based oligomers to be used as surgical adhesives

Santos

Marques

Alves

et al. 2015

Reactive and Functional Polymers

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“…Hydrogels formed by light irradiation are an important family of chemically cross-linked hydrogels for cell encapsulation. The photocross-linking process involves the presence of photoinitiator compounds whose chemical nature determines the reaction rate and the wavelength of absorption [50]. When irradiated by light, typically in the UV range, the photoinitiators form free radicals that react with functional groups of the polymer backbone forming intermolecular bonds.…”

Section: Gelling Mechanismmentioning

confidence: 99%

Natural polymers for the microencapsulation of cells

Gasperini

Mano

Reis

2014

J. R. Soc. Interface.

513

403

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The encapsulation of living mammalian cells within a semi-permeable hydrogel matrix is an attractive procedure for many biomedical and biotechnological applications, such as xenotransplantation, maintenance of stem cell phenotype and bioprinting of three-dimensional scaffolds for tissue engineering and regenerative medicine. In this review, we focus on naturally derived polymers that can form hydrogels under mild conditions and that are thus capable of entrapping cells within controlled volumes. Our emphasis will be on polysaccharides and proteins, including agarose, alginate, carrageenan, chitosan, gellan gum, hyaluronic acid, collagen, elastin, gelatin, fibrin and silk fibroin. We also discuss the technologies commonly employed to encapsulate cells in these hydrogels, with particular attention on microencapsulation.

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Photocrosslinkable Polymers for Biomedical Applications

Cited by 20 publications

References 68 publications

RETRACTED: A Bio Polymeric Adhesive Produced by Photo Cross-Linkable Technique

RETRACTED: A Bio Polymeric Adhesive Produced by Photo Cross-Linkable Technique

Synthesis, functionalization and characterization of UV-curable lactic acid based oligomers to be used as surgical adhesives

Natural polymers for the microencapsulation of cells

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