Photochemically synthesized heparin-based silver nanoparticles: an antimicrobial activity study

Nondegradable Antimicrobial Silver-Based Perovskite

“…Indeed, an extensive data analysis did not reveal a clear-cut dependence of MIC values on the particle sizes. − However, there have been suggestions that an increased level of contact between microbial cells and nanoparticles through the higher surface area (densities of edges and corner sites) is correlated with higher levels of antimicrobial activity. , There is some direct evidence for supporting this hypothesis, that is, antimicrobial effect through contact. Recently, Del Pilar Rodriguez-Torres and Díaz–Torres synthesized heparin-based silver nanoparticles that exhibited no antimicrobial activity. They speculated that the heparin layer on the nanoparticles provided them with a negative charge, and accordingly, the repulsive electrical forces did not permit any contact between the nanoparticles and the cell wall.…”