Photocatalytic degradation of rosuvastatin: Analytical studies and toxicity evaluations

Kinetic study of the degradation/mineralization of aqueous solutions contaminated with Rosuvastatin drug by Electro-Fenton: Influence of experimental parameters

“…This behavior is an accordance with a previous study concerning the degradation of ROS in aqueous solutions [20] [58,59]. The value of the apparent rate constant K app is found to be 0.32 min -1 (R² = 0.992) at 30 mA, 0.53 min -1 (R² = 0.998) at 60 mA, 0.55 min -1 (R² = 0.991) at 100 mA, and 1.02 min -1 (R² = 0.996) at 300 mA.…”

“…There are a few studies concerning the degradation of rosuvastatin but none approached the EF process; we have found photocatalytic degradation of rosuvastatin using ZnO catalyst in suspension [58] and in demineralised water [20]. These studies demonstrated that ROS is classified as a moderately degradable compound and the effectiveness of this process can be influenced by the presence of dissolved Zno [20].…”

Identification of transformation products of rosuvastatin in water during ZnO photocatalytic degradation through the use of associated LC–QTOF–MS to computational chemistry

“…The correlation coefficient (r) was 0.9955, confirming the adequacy of the pseudo-first order model to describe the kinetics of RST degradation. This behavior is in accordance with a previous study concerning the photocatalytic degradation of RST in aqueous solutions containing ZnO in suspension [23], in which the RST content was analyzed by using spectrophotometry technique. In that study the kinetic evaluation showed a pseudo-first order degradation behavior, which was the same kinetic profile as obtained by employing the LC-QTOF-MS technique in this work.…”

“…In previous research, studies of acute toxicity testing using D. magna for evaluating the toxicity of the untreated RST solution as the effluent generated by the ZnO photocatalysis [23] showed an increase in toxicity with increasing irradiation timeframes. This result suggests that the TPs formed upon irradiation of RST are more toxic than is RST itself.…”

Treatment of statins drug (pravastatin and rosuvastatin) in water by electro-Fenton process: Kinetics of degradation/mineralization and optimization of experimental conditions for a biological post-treatment

“…Recently, electrochemical methods based on the Fenton reaction such as electro-Fenton (EF) have shown promising results in the degradation of organic matter in water through their simplicity, high efficiency and relatively low cost 22,23 . This has been demonstrated for several pollutants, including phenols 24,25 , synthetic dyes 26 , herbicides and pesticides 27,28 and drugs [29][30][31][32][33] .…”