Photoallergy

Epstein, John H.

doi:10.1001/archderm.1972.01620140081025

Cited by 86 publications

(8 citation statements)

References 77 publications

(3 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Symptoms of OLAQinduced photoallergy resemble those of QUIN [31]. Generally, a photochemical reaction of a xenobiotic resulting in damage of, or irreversible binding to an endogenous protein, is considered as an initial step, which may lead to a photoallergic response [39][40][41].…”

Section: Growth-promoting Properties and Toxicity Of Quinoxaline 14-mentioning

confidence: 99%

Quinoxaline 1,4-Dioxide: A Versatile Scaffold Endowed With Manifold Activities

Carta

Corona²,

Loriga

2005

CMC

136

View full text Add to dashboard Cite

Since 1940s, Quinoxaline 1,4-dioxides (QdNO's) are known as potent antibacterial agents, and subtherapeutic levels have been used to promote growth and improve efficiency of feed conversion in animal feed. They have also shown a selective cytotoxicity against hypoxic cells present in solid tumours. Furthermore, recent studies have put in evidence that QdNO's are endowed with antitubercular, antiprotozoal and anticandida activities. On the other hand, several authors have reported about photoallergic and mutagenic effects of some derivatives. QdNO's may also cause the development of antibiotic-resistant bacteria and influence the horizontal transfer of virulence genes between bacteria. In this review article we report the biological properties, the mode of action and Structure Activity Relationship (SAR) studies of the QdNO derivatives. Furthermore, some cytogenetic and genotoxic effects, classical and more recent method of synthesis, the quinoxaline 1,4-dioxides, and some of their most important reactions, were also reported.

show abstract

Section: Growth-promoting Properties and Toxicity Of Quinoxaline 14-mentioning

confidence: 99%

Quinoxaline 1,4-Dioxide: A Versatile Scaffold Endowed With Manifold Activities

Carta

Corona²,

Loriga

2005

CMC

136

View full text Add to dashboard Cite

show abstract

“…Bei der photoallergischen Kontaktdermatitis handelt es sich ähnlich wie bei der allergischen Kontaktdermatitis um eine T-Zell-vermittelte Typ-IV-Reaktion der Haut als Folge der gleichzeitigen Einstrahlung von UV-Licht und eines Kontaktes mit einem topischen Photoallergen [5,11,12]. Ähnlich wie bei der allergischen Kontaktdermatitis ist bei der photoallergischen Kontaktdermatitis vor Ausbruch der Erkrankung eine Sensibilisierungsphase erforderlich.…”

Section: Photoallergische Kontaktdermatitisunclassified

Histopathologie der Photodermatosen

Megahed

Schaller²

2006

Hautarzt

View full text Add to dashboard Cite

Photodermatoses are skin disorders which result from abnormal response to ultraviolet (UV) radiation. Photodermatoses include the following disorders: polymorphic light eruption, hydroa vacciniforme, solar urticaria, actinic prurigo, acute actinic dermatosis, solar dermatosis, phototoxic dermatitis and photoallergic dermatitis. The histopathology of these disorders will be presented and its role in making the diagnosis will be discussed.

show abstract

“…Photoallergic contact dermatitis is a cutaneous cell-mediated Type IV hypersensitivity reaction to exogenous drugs in the presence of radiant energy [49][50][51][52][53][54][55]. Wavelengths in the UVA range are mainly responsible for such photoallergic reactions.…”

Section: Pbotosensitivitymentioning

confidence: 99%

“…In both cases, this elicits a cell-mediated immune response. This manifests clinically as eczematous dermatitis [52][53][54]57] characterized by erythema, edema, vesiculation, oozing and pruritus. The photoallergic reactions do not occur at first exposure to the photoallergen, but require a latent period during which sensitization occurs.…”

Section: Pbotosensitivitymentioning

confidence: 99%