Photoacoustic Tomography

Abstract

The paper contains a simple approach to reconstruction in Thermoacoustic and Photoacoustic Tomography. The technique works for any geometry of point detectors placement and for variable sound speed satisfying a non-trapping condition. A uniqueness of reconstruction result is also obtained.

Technical Note: Thermoacoustic imaging of hemorrhagic stroke: A feasibility study with a human skull

“…(c) intercepts the profile at points A, B, C, and D. Thus, the spatial resolution can be approximated as , where d is the diameter of the copper wire; hence the spatial resolution is estimated to be about 0.9 mm. The spatial resolution is primarily limited by the pulse width of the microwave generator …”

“…However, CT and MRI systems are quite bulky and often not mobile. Thermoacoustic imaging (TAI) is an emerging modality capable of high microwave contrast and high ultrasound resolution . In particular, TAI is relatively portable and mobile, making it uniquely suited for its use in an ambulance.…”

Photoacoustic molecular imaging using combined acupuncture and gold nanorods as a composite contrast agent

“…[1][2][3][4][5][6][7] This in vivo brain functional imaging technique has the following unique advantages: (1) it is an noninvasive imaging mode which is conducted in accordance with ethical principles; (2) animals can maintain normal physiological activity during imaging; (3) it has adequate spatial resolution (up to tens of m), temporary resolution (up to tens of ms) and limited depth of penetration (up to several mm, with intact scalp) in monitoring the brain; (4) it provides high-resolution functional information, such as hemoglobin and blood oxygenation levels relevant to describing physiology and pathology. 6,[8][9][10][11][12][13][14][15][16][17][18][19][20] PAT of small animal brain has successfully been implemented. 3,[8][9][10][11][12][13] In these studies, PAT was used for mapping the microvascular network of a mouse brain with the hemodynamic activities when the scalp and skull were intact.…”

Fan‐shaped scanning approach for miniaturized photoacoustic tomography

“…Photoacoustic imaging (PAI) is one of the fastest growing biomedical optical imaging techniques capable of providing nonionizing and noninvasive imaging of tissue absorption with high spatial resolution, and has been demonstrated in biological and clinical applications . In general, PAI is classified into photoacoustic microscopy (PAM) and photoacoustic tomography (PAT), according to different implementation strategies and image reconstruction algorithms.…”