Photo-immobilization of a phospholipid polymer for surface modification

Synthesis of photoreactive pullulan for surface modification

“…Contact angle measurement was performed as previously reported [26]. The unpatterned sample was placed on the holder of a CA-W Automatic Contact Angle Meter (Kyowa Interface, Co. Ltd., Saitama, Japan) and a drop of water (0.4 mL) was put on the sample surface.…”

Cartilage-mimicking, High-density Brush Structure Improves Wear Resistance of Crosslinked Polyethylene: A Pilot Study

“…MPC polymers are one of the most common biocompatible and hydrophilic polymers studied thus far and have potential applications in a variety of fields, including biology, biomedical science, and surface chemistry [9,10,18,19,37,39,40,43]. Surface modifications of MPC polymers for other medical devices have suppressed biologic reactions when they were put in contact with living organisms [9,18,43] and are now clinically used on the surfaces of intravascular stents [19,37], soft contact lenses [39], and artificial lungs and hearts [15,40] under the authorization of the US Food and Drug Administration.…”

Gelatinase-stimuli strategy enhances the tumor delivery and therapeutic efficacy of docetaxel-loaded poly(ethylene glycol)-poly(ε-caprolactone) nanoparticles

“…5 Another new targeting strategy in development is employing stimuli-sensitive nanocarriers, such as thermo-sensitive micelles, 6 magnetic nanoparticles, 7 and photoresponsive polymers. 8 The structures of these nanocarriers could be transformed by external or internal triggering elements, facilitating drug release from nanoparticles or interacting with the tumor cells targetedly. 9 Although these reported nano-drugs are sensitive enough in laboratory research, limitations for clinical applications still exist.…”