Phosphatidylinositol 4-Kinase Activation Is an Early Response to Salicylic Acid in Arabidopsis Suspension Cells

Krinke, Ondřej; Ruelland, Éric; Valentová, Olga; Vergnolle, Chantal; Renou, Jean-Pierre; Taconnat, Ludivine; Flemr, Matyáš; Burketová, Lenka; Zachowski, Alain

doi:10.1104/pp.107.100842

Cited by 112 publications

(127 citation statements)

References 47 publications

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“…This result is in agreement with the fact that the CCT activity in protein bodies of fl oury-2 maize also increases when UPR is activated (Shank et al, 2001). Furthermore, Arabidopsis thaliana culture cells treated with salycilic acid leads to the upregulation of the ER stress markers BiP3 and PDI as well as the PI 4-kinase (Krinke et al, 2007), enzyme that is also activated in fl oury-2.…”

Section: Figure 2 Schematic Representation Of the Involvement Of Uprsupporting

confidence: 78%

The physiological role of the unfolded protein response in plants

Moreno

Orellana

2011

Biol. Res.

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SUMMARYUnfolded protein response (UPR) is a signaling mechanism activated by misfolded protein accumulation in the endoplasmic reticulum. It is a widespread process that has been described in organisms ranging from yeasts to mammals. In recent years, our understanding of UPR signaling pathway in plants has advanced. Two transcription factors from Arabidopsis thaliana have been reported to function as the sensor/ transducer of this response (AtbZIP60 and AtbZIP28). They seem to be involved in both heat and biotic stress. Furthermore, overexpression of one of them (AtbZIP60) produces plants with a higher tolerance for salt stress, suggesting that this transcription factor may play a role in abiotic stress. Furthermore, some data suggest that crosstalk between genes involved in abiotic stress and UPR may also exist in plants. On the other hand, UPR is related to programmed cell death (PCD) in plants given that that triggering UPR results in induction of PCD-related genes. This article reviews the latest progress in understanding UPR signaling in plants and analyzes its relationship to key processes in plant physiology.

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Section: Figure 2 Schematic Representation Of the Involvement Of Uprsupporting

confidence: 78%

The physiological role of the unfolded protein response in plants

Moreno

Orellana

2011

Biol. Res.

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“…Wortmannin at high concentrations (above 30 mM) also inhibited phosphatidylinositol-4-phosphate (PI4P) and phosphatidylinositol-4,5-bisphosphate [PI(4,5)P 2 ] production by inhibiting type III PI4 kinase (Krinke et al, 2007). Because PI4P and PI(4,5)P 2 regulate both vesicle trafficking and the actin cytoskeleton in animal cells (Balla and Balla, 2006), we were concerned that wortmannin treatment might not be specific.…”

Section: Optimization Of Pharmacological Treatments On Arabidopsis Pomentioning

confidence: 99%

Interdependence of Endomembrane Trafficking and Actin Dynamics during Polarized Growth of Arabidopsis Pollen Tubes

Zhang

Lee

et al. 2010

Plant Physiology

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During polarized growth of pollen tubes, endomembrane trafficking and actin polymerization are two critical processes that establish membrane/wall homeostasis and maintain growth polarity. Fine-tuned interactions between these two processes are therefore necessary but poorly understood. To better understand such cross talk in the model plant Arabidopsis (Arabidopsis thaliana), we first established optimized concentrations of drugs that interfere with either endomembrane trafficking or the actin cytoskeleton, then examined pollen tube growth using fluorescent protein markers that label transport vesicles, endosomes, or the actin cytoskeleton. Both brefeldin A (BFA) and wortmannin disturbed the motility and structural integrity of ARA7-but not ARA6-labeled endosomes, suggesting heterogeneity of the endosomal populations. Disrupting endomembrane trafficking by BFA or wortmannin perturbed actin polymerization at the apical region but not in the longitudinal actin cables in the shank. The interference of BFA/wortmannin with actin polymerization was progressive rather than rapid, suggesting an indirect effect, possibly due to perturbed endomembrane trafficking of certain membrane-localized signaling proteins. Both the actin depolymerization drug latrunculin B and the actin stabilization drug jasplakinolide rapidly disrupted transport of secretory vesicles, but each drug caused distinct responses on different endosomal populations labeled by ARA6 or ARA7, indicating that a dynamic actin cytoskeleton was critical for some steps in endomembrane trafficking. Our results provide evidence of cross talk between endomembrane trafficking and the actin cytoskeleton in pollen tubes.

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“…Furthermore, SAIGs coding for endoplasmic reticulumlocalized proteins associated to the protein secretory machinery and for WRKY transcription factors involved in PR-1 activation, have been recently identified as primary targets of NPR1 involved in defense (Wang et al 2005. Recently, two studies analyzing the response of Arabidopsis to short treatments with SA were published (Thibaud-Nissen et al 2006;Krinke et al 2007). One was performed in Arabidopsis cell suspensions and allowed the identification of SAIGs associated to the early activation of phosphatidylinositol 4-kinase (Krinke et al 2007).…”

Section: Introductionmentioning

confidence: 99%

“…Recently, two studies analyzing the response of Arabidopsis to short treatments with SA were published (Thibaud-Nissen et al 2006;Krinke et al 2007). One was performed in Arabidopsis cell suspensions and allowed the identification of SAIGs associated to the early activation of phosphatidylinositol 4-kinase (Krinke et al 2007). The other study was performed in Arabidopsis plants and was oriented to identifying targets of TGA2 factor (ThibaudNissen et al 2006).…”

Section: Introductionmentioning

confidence: 99%

Early genomic responses to salicylic acid in Arabidopsis

et al. 2009

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Salicylic acid (SA) is a stress-induced hormone involved in the activation of defense genes. Here we analyzed the early genetic responses to SA of wild type and npr1-1 mutant Arabidopsis seedlings, using Complete Arabidopsis Transcriptome MicroArray (CATMAv2) chip. We identified 217 genes rapidly induced by SA (early SAIGs); 193 by a NPR1-dependent and 24 by a NPR1-independent pathway. These two groups of genes also differed in their functional classification, expression profiles and over-representation of cis-elements, supporting differential pathways for their activation. Examination of the expression patterns for selected early SAIGs from both groups indicated that their activation by SA required TGA2/5/6 subclass of transcription factors. These genes were also activated by Pseudomonas syringae pv. tomato AvrRpm1, suggesting that they might play a role in defense against bacteria. This study gives a global idea of the early response to SA in Arabidopsis seedlings, expanding our knowledge about SA function in plant defense.

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Phosphatidylinositol 4-Kinase Activation Is an Early Response to Salicylic Acid in Arabidopsis Suspension Cells

Cited by 112 publications

References 47 publications

The physiological role of the unfolded protein response in plants

The physiological role of the unfolded protein response in plants

Interdependence of Endomembrane Trafficking and Actin Dynamics during Polarized Growth of Arabidopsis Pollen Tubes

Early genomic responses to salicylic acid in Arabidopsis

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