Phosphapalladacycle-Catalyzed Heck Reactions for Efficient Synthesis of Trisubstituted Olefins: Evidence for Palladium(0) Intermediates

Tetradentate N2O2 Chelated Palladium(II) Complexes: Synthesis, Characterization, and Catalytic Activity towards Mizoroki‐Heck Reaction of Aryl Bromides

“…In the case of an organic base, low conversion was also observed for Et 3 N (entries 1 and 17) which may due in part to steric effects exerted by competitive coordination of amine to palladium center [38,39]. It may also in part due to the formation of gaseous Et 3 N at 120 ∘ C that may lead to poor contact with the reaction mixture.…”

Active Palladium Colloids via Palladacycle Degradation as Efficient Catalysts for Oxidative Homocoupling and Cross-Coupling of Aryl Boronic Acids

“…Although the synthetic utility of palladacycles has been well explored, for many years, the unique reactivity profile of these catalytic systems was attributed to the presence of either the Pd­(II)/Pd­(IV) , or Pd(0)/Pd­(II) catalytic cycle. However, the noteworthy work by Jutand and co-workers needs a special mention in this regard, providing useful insight into the possible mechanistic intermediates in these processes.…”

Visible-Light-Driven Palladium-Catalyzed Radical Tandem Dearomatization of Indoles with Unactivated Alkenes

“…Additionally, naphthalene and ethylenedioxy styrene were well tolerated ( 3m and 3n , respectively). When α-methylstyrene was applied in this photoredox reaction, only the disubstituted double bond 3o was formed . Furthermore, electron-deficient 4-trifluoromethylstyrene and 2-vinylpyridine afforded products 3p and 3q , respectively, in reasonable yields, while other electron-deficient alkenes, including 4-nitrostyrene and acrylate ester, were not compatible with this protocol ( 3r and 3s , respectively).…”

“…When α-methylstyrene was applied in this photoredox reaction, only the disubstituted double bond 3o was formed. 15 Furthermore, electron-deficient 4trifluoromethylstyrene and 2-vinylpyridine afforded products 3p and 3q, respectively, in reasonable yields, while other electron-deficient alkenes, including 4-nitrostyrene and acrylate ester, were not compatible with this protocol (3r and 3s, respectively). Next, we investigated the reactivity of N-acylindoles 1 with styrene 2a in this visible-light-driven Pd-catalyzed dearomatization process (Table 3).…”