Phoneme Discrimination in Schizophrenia

Kugler, Barbara T.; Caudrey, David J.

doi:10.1192/bjp.142.1.53

Cited by 23 publications

(16 citation statements)

References 16 publications

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“…This finding may have a certain level of specificity regarding other clinical populations. Studies of categorical perception in schizophrenia (Cienfuegos, March, Shelley, & Javitt, 1999;Kugler & Caudrey, 1983), Alzheimer disease (Saumier et al, in revision) and developmental dyslexia (Serniclaes, SprengerCharolles, Carre, & Demonet, 2001) have consistently revealed anomalies both in discrimination and classification curves, whereas in our study individuals with autism show a typical classification curve associated with an atypical discrimination curve.…”

Section: Increased Autonomy Of Processing Levels and Models Of Autismcontrasting

confidence: 61%

Atypical Categorical Perception in Autism: Autonomy of Discrimination?

Soulières

Mottron

Saumier

et al. 2006

J Autism Dev Disord

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A diminished top-down influence has been proposed in autism, to account for enhanced performance in low-level perceptual tasks. Applied to perceptual categorization, this hypothesis predicts a diminished influence of category on discrimination. In order to test this hypothesis, we compared categorical perception in 16 individuals with and 16 individuals without high-functioning autism. While participants with and without autism displayed a typical classification curve, there was no facilitation of discrimination near the category boundary in the autism group. The absence of influence of categorical knowledge on discrimination suggests an increased autonomy of low-level perceptual processes in autism, in the form of a reduced top-down influence from categories toward discrimination.

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Section: Increased Autonomy Of Processing Levels and Models Of Autismcontrasting

confidence: 61%

Atypical Categorical Perception in Autism: Autonomy of Discrimination?

Soulières

Mottron

Saumier

et al. 2006

J Autism Dev Disord

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“…For example, Lawson et al (1964) documented deficits in speech comprehension in schizophrenia that reflected inability to take advantage of speech regularities, whereas Kugler & Caudrey (1983) showed deficits specifically in processing of phonemes (e.g., /ba/ versus /da/). Nevertheless, these early findings were not strongly pursued until recent years.…”

Section: Bottom-up Contributions To Impaired Processing In Schizophreniamentioning

confidence: 99%

When Doors of Perception Close: Bottom-up Models of Disrupted Cognition in Schizophrenia

Javitt

2009

Annu. Rev. Clin. Psychol.

458

386

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Schizophrenia is a major mental disorder that affects approximately 1% of the population worldwide. Cognitive deficits are a key feature of schizophrenia and a primary cause of long-term disability. Current neurophysiological models of schizophrenia focus on distributed brain dysfunction with bottom-up as well as top-down components. Bottom-up deficits in cognitive processing are driven by impairments in basic perceptual processes that localize to primary sensory brain regions. Within the auditory system, deficits are apparent in elemental sensory processing, such as tone matching following brief delay. Such deficits lead to impairments in higher-order processes such as phonological processing and auditory emotion recognition. Within the visual system, deficits are apparent in functioning of the magnocellular visual pathway, leading to higher-order deficits in processes such as perceptual closure, object recognition, and reading. In both auditory and visual systems, patterns of deficit are consistent with underlying impairment of brain N-methyl-d-aspartate receptor systems.

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“…In PSZ, deficits in different stages of auditory stimulus and speech processing have been described (Kugler and Caudrey, 1983;Javitt, 2000;Vercammen et al, 2008;Naatanen and Kahkonen, 2009), which appear to contribute to higher-order cognitive deficits (Javitt et al, 1999;Kawakubo et al, 2006;Leitman et al, 2010). A computerized training approach that places particular emphasis on early sensory processing (Posit Science, Duncan, SC) and that improved auditory processing and oral language abilities in dyslexia (Temple et al, 2003) has been adapted for use in PSZ.…”

Section: The Treatment Of Cognitive Dysfunction In Schizophreniamentioning

confidence: 97%