Pheochromocytoma of the urinary bladder: A broad clinical spectrum

Pheochromocytoma of the urinary bladder - a case report

“…Some authors consider invasion into surrounding organs and tissues or lymph node involvement as a criteria for malignancy 12,13 . The presence of necrosis, angiolymphatic invasion, increase of mitosis and DNA ploidia indicate the malignant potential of the pheochromocytoma 1,5,[14][15][16][17][18][19] . The current literature reported clinical signs range from the micturition attacks of headaches, palpitations, visual disturbances, tachycardia, sustained or paroxysmal hypertension, hematuria, dysuria, suprapubic pain or sweating after voiding 20,21 .…”

“…The current literature reported clinical signs range from the micturition attacks of headaches, palpitations, visual disturbances, tachycardia, sustained or paroxysmal hypertension, hematuria, dysuria, suprapubic pain or sweating after voiding 20,21 . In around 17% of cases tumors are hormone inactive with practically no symptoms or can be presented only by pain or hematuria 13,19,20 . Only 40% of cases are preoperatively diagnosed, and the majority got adequate diagnosis after bladder surgery 21 .…”

Paraganglioma of the Urinary Bladder

“…The clinical presentation of bladder paragangliomas may include attacks of headache, sweating, palpitations and fainting triggered by micturition, bladder distension and even sexual intercourse [6], Episodic or sustained hypertyension has been described in 65-80% of the pa tients, while painless hematuria is less common [2][3][4].…”

“…The majority of these neoplasms secrete catecholamines and more than half of the patients present with hypertension. Common systemic symptoms are episodes of headache, palpitations and sweating, while specific urinary symptoms are dysuria and hematuria [3][4][5][6].…”

A Case of Pheochromocytoma of the Urinary Bladder in a Long-Term Hemodialysis Patient

“…Thus, ours is the first case of pheochromocytoma of the urinary bladder in a HD patient. Raper et al [13] reported that, in cases of pheochromocytoma of the urinary bladder, micturition-induced hypertensive spells or hema turia were observed in 63% of patients, but spells initiated by defecation were very rare (only 3%).…”