Phenothiazine-induced extrapyramidal dysfunction in the neonate

Tamer, Akram; McKey, Robert M.; Arias, Doralys; Worley, Lee; Fogel, Bernard J.

doi:10.1016/s0022-3476(69)80275-1

Cited by 53 publications

(10 citation statements)

References 3 publications

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“…[51][52][53] Centrally acting opioid analgesics such as codeine and propoxyphene should be used cautiously and used only when necessary. [56][57][58][59][60] Prolonged or high-dose opioids late in pregnancy significantly increases the risk of these defects occuring.…”

Section: Narcotics Opioids and Peripherally Acting Agentsmentioning

confidence: 99%

Dermatologic Surgery and the Pregnant Patient

Richards

Stasko

2002

Dermatologic Surgery

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background. Because of concerns about potential harm to the mother or fetus, dermatologic surgeons are frequently hesitant to perform cutaneous surgery on pregnant patients. objective. To review the relevant physiologic changes during pregnancy, appropriate preparation for and timing of procedures, and drug safety. methods. A literature review was performed of dermatologic and nondermatologic journals discussing physiology, surgery, and drug safety in the pregnant patient. results. Special positioning is required for the pregnant patient during surgery. Low doses of most local anesthetics with epinephrine as well as nitrous oxide less than 50% are safe to use during pregnancy. Sedatives and opioids are potential teratogens and should be avoided. Safe antibiotics to use during skin surgery in pregnancy include penicillins, cephalosporins, and nonestolate erythromycin. If necessary, lymph node dissections under general anesthesia in the pregnant melanoma patient should occur during the second trimester. conclusion. With appropriate preparation, safe and successful cutaneous surgery can be performed on the pregnant patient. Respiratory ChangesBy term, there is an increase in tidal volume and minute respiration to 30-40% due to increased fetal K.A. Richards, MD and T. Stasko, MD have indicated no significant interest with commercial supporters.

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Section: Narcotics Opioids and Peripherally Acting Agentsmentioning

confidence: 99%

Dermatologic Surgery and the Pregnant Patient

Richards

Stasko

2002

Dermatologic Surgery

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“…Druginduced extrapyramidal reactions are very rare in neonates but are sometimes reported in babies born to mothers who were on anti-psychotic drugs for prolonged periods during pregnancy [5][6][7] .…”

Section: Discussionmentioning

confidence: 99%

Maternal medication causing drug dystonia in a newborn: placental transfer of drugs

Gokhale¹,

Panchakshari²

2004

Journal of Maternal-Fetal and Neonatal Medicine

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“…These have included TCA "withdrawal syndromes" with characteristic symptoms of jitteriness, irritability, and seizures following exposure to these agents during labor and delivery (Eggermont, 1973;Schimmel et al, 1991;Webster, 1973;Cowe et al, 1982). Symptoms of functional bowel obstruction, and urinary retention presumably secondary to anticholinergic effects of tricyclics have also been reported (Shearer et al, 1972;Tamer et al, 1969). While several animal studies describe a spectrum of behavioral abnormalities during the first 30 days of life following prenatal exposure to tricyclic antidepressants (Auerbach et al, 1992;Ali et al, 1986;Del Rio et al, 1988;Coyle, 1975;File and Tucker, 1984;Jason et al, 1981;DeCeballos et al, 1985) no systematically derived data are available regarding long-term sequelae of such exposure in humans.…”

Section: A Tricyclic Antidepressantsmentioning

confidence: 99%

Pharmacologic treatment of depression in women: PMS, pregnancy, and the postpartum period

Cohen¹

1998

Depress. Anxiety

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Phenothiazine-induced extrapyramidal dysfunction in the neonate

Cited by 53 publications

References 3 publications

Dermatologic Surgery and the Pregnant Patient

Dermatologic Surgery and the Pregnant Patient

Maternal medication causing drug dystonia in a newborn: placental transfer of drugs

Pharmacologic treatment of depression in women: PMS, pregnancy, and the postpartum period

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