Phenological changes in triterpenic and phenolic composition of Thymus L. species

Isodon rugosus (Wall. ex Benth.) Codd In Vitro Cultures: Establishment, Phytochemical Characterization and In Vitro Antioxidant and Anti-Aging Activities

“…TDZ at lower concentration (1.0 mg/L) resulted in optimal production of PA (Ir#1), while higher concentration (3.0 mg/L) of TDZ favored maximum accumulation of CA (Ir#6) and OA (Ir#5), but interestingly the nature of the initial explant differed between these two conditions: leaf-derived callus for optimal CA production vs. stem-derived callus for optimal OA accumulation. CA and RA are regarded as major phenolic metabolites of plants from Lamiaceae family [47,48]. In this study, we endeavor an effort to report in vitro culture condition for accumulation and production of these phenolics and pentacyclic triterpenes metabolites in I. rugosus callus culture.…”

Targeting Oxidative Stress Reduction and Inhibition of HDAC1, MECP2, and NF-kB Pathways in Rats With Experimentally Induced Hyperglycemia by Administration of Thymus marshallianus Willd. Extracts

“…Thymus (thyme) is one of the most important genus belonging to the Lamiaceae family (Niculae et al, 2019). This family is known worldwide for its traditional uses, in the treatment of different pathologies, being also used since ancient times for their importance as aromatic plants (Nabavi et al, 2015), that are assigned to their composition in essential oils (Tohidi et al, 2019) and phenolic compounds (Raudone et al, 2017). Thymus marschallianus Willd.…”

“…(TM) is a species belonging to the Thymus genus which presents numerous chemovarieties: thymol, carvacrol, thymol/carvacrol, geraniol and carveole, that are related to the composition of its essential oils (Salehi et al, 2019). Besides the important number of volatile compounds, the species is also known for its composition in phenolic compounds, which are also responsible for its biological activity (Raudone et al, 2017). Among these compounds, the most important appears to be rosmarinic acid (RA), which is found in large amounts in the flowering aerial parts of the species (Niculae et al, 2019).…”

Phytochemical Profiles of Alpine Plant Horminum pyrenaicum L. during Phenological Growth Stages

“…HPLC Analysis was performed using a ‘Waters e2695 Alliance system’ (Waters, Milford, MA, USA) with a photodiode array detector ‘Waters 2998’ according to the HPLC‐PDA method for phenolic compounds and HPLC‐PDA method for triterpenic compounds reported by Raudone et al …”

“…HPLC Analysis was performed using a 'Waters e2695 Alliance system' (Waters, Milford, MA, USA) with a photodiode array detector 'Waters 2998' according to the HPLC-PDA method for phenolic compounds and HPLC-PDA method for triterpenic compounds reported by Raudone et al [47] Sample Preparation and Determination of Essential Oil Compounds by GC/MS Essential oils were obtained by hydrodistillation from air-dried above-ground parts (50 g) in a Clevenger apparatus for 2 h according to the European Pharmacopoeia. [48] The essential oil content was expressed as v/w% for the dry material.…”