Phenolic glycosides from Rhodohypoxis baurii

Matsuo, Yukiko; Tachikawa, Fumito; Mimaki, Yoshihiro

doi:10.1007/s11418-010-0465-y

Cited by 3 publications

(1 citation statement)

References 10 publications

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“…Hypoxis species are known to produce a variety of phytoglycosides, including several norlignan glycosides (Marini-Bettolo et al, 1982;Drewes et al, 1984;Galeffi et al, 1989;Sibanda et al, 1991) and phenolic glycosides (Cheng et al, 2009;Matsuo et al, 2011). Hypoxoside, a norlignan diglycoside, is the best known of these metabolites, since its aglycone, rooperol, is believed to play an important role in the medicinal properties of Hypoxis (Albrecht, 1996).…”

Section: Introductionmentioning

confidence: 99%

New phytochemicals from the corms of medicinally important South African Hypoxis species

Bassey

Viljoen

Combrinck

et al. 2014

Phytochemistry Letters

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Hypoxis species (Hypoxidaceae) are amongst the most widely used medicinal plants in southern Africa. Although the phytochemistry of Hypoxis hemerocallidea has been extensively investigated, little is known regarding the secondary metabolites of the other indigenous species, including Hypoxis colchicifolia and Hypoxis galpinii. Two new phenolic glycosides, 3-hydroxy-4-O-b-D-glucopyranosylbenzaldehyde and 1,5-bis(3,4-dihydroxyphenyl)-1,2-dihydroxy-4-pentyne-2-p-coumaroyl-b-D-glucopyranoside were isolated from corms of H. colchicifolia and H. galpinii, respectively. The norlignan glycosides (hypoxoside, dehydroxy hypoxoside and bis-dehydroxy hypoxoside) were isolated from H. colchicifolia for the first time, using high performance countercurrent chromatography and elucidated by 1D and 2D NMR as well as high resolution MS. In addition, geraniol glycoside and b-sitosterol, previously described in Hypoxidaceae, were isolated from the same species. The presence of hypoxoside in all three species investigated indicated that the interchangeable use of Hypoxis species by communities has some merit. Establishing the biological properties of the new constituents will provide more insight into the medicinal value of the genus.

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