2016
DOI: 10.1111/jphp.12660
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Phenolic compounds alone or in combination may be involved in propolis effects on human monocytes

Abstract: Propolis activated human monocytes, and acids were involved differently in propolis activity.

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Cited by 27 publications
(26 citation statements)
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“…[42] The existence of a complex mixture of bioactive compounds in plant extracts and their mutual interactions are common explanations for the overall observed antimicrobial activity (as well as for some other demonstrated pharmacological effects). [42,43] It is possible that some antimicrobial effects may lie in other plant constituents such as tannins (e.g. tannic acid), which were previously demonstrated to possess such properties.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…[42] The existence of a complex mixture of bioactive compounds in plant extracts and their mutual interactions are common explanations for the overall observed antimicrobial activity (as well as for some other demonstrated pharmacological effects). [42,43] It is possible that some antimicrobial effects may lie in other plant constituents such as tannins (e.g. tannic acid), which were previously demonstrated to possess such properties.…”
Section: Discussionmentioning
confidence: 99%
“…Potential thiosulphinates from Allium extracts react with free SH groups of intracellular enzymes and affect intracellular processes and cell communication . The existence of a complex mixture of bioactive compounds in plant extracts and their mutual interactions are common explanations for the overall observed antimicrobial activity (as well as for some other demonstrated pharmacological effects) . It is possible that some antimicrobial effects may lie in other plant constituents such as tannins (e.g.…”
Section: Discussionmentioning
confidence: 99%
“…The concentration of caffeic acid correlates positively with the ability of B. dracunculifolia to inhibit cytokine production in murine macrophages . Caffeic acid is an important mediator of the immunomodulating action of the aqueous extract of Tournefortia sarmentosa and propolis towards neutrophils and monocytes, respectively. We have previously reported that the caffeic acid concentration, but not the AME concentration in BdE, positively correlates with inhibition of ROS generation in human neutrophils .…”
Section: Introductionmentioning
confidence: 90%
“…According to Heneczkowski and colleagues [48] the ranges 1612-1598, 1570-1560 and 1488-1452 cm −1 are typical for the vibrations of the aromatic ring, characteristic of polyphenols contained in extracts. The sharp peaks in the region 1320-1000 cm −1 related to carbon-oxygen bonds (C-O) in the ether, esters and carboxylic acids are indicative of a wide variety of metabolites, such as tannins, flavonoids and anthraquinones, among others [49,50].…”
Section: Fourier Transform Infrared Spectroscopy (Ftir)mentioning
confidence: 99%