Phenolic Compound Content, Profiles and Antioxidant Activities of Amaranthus Hybridus (Pigweed), Brachiaria Brizantha (Upright Brachiaria) and Panicum Maximum (Guinea Grass)

Chitindingu, Kudakwashe; Ndhlala, A.R.; Chapano, C.; Benhura, M. A. N.; Muchuweti, Maud

doi:10.1111/j.1745-4514.2007.00108.x

Cited by 29 publications

(21 citation statements)

References 17 publications

(19 reference statements)

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“…To compare this activity with those of other plants described in the literature, the antioxidant activity determinate by DPPH test was expressed as IC 50 . The IC 50 values of S. rebaudiana extracts were 2.9, 5.0 and 9.26 mg/mL respectively for E.O, WE and MWE; compared to Becium dhofarense Sebald (IC 50 : 11.0 mg/mL), Ficus lutea Vahl (IC 50 : 11.9 mg/mL), Cordia (Chitindingue, Ndhlala, Chapano, Benhura, & Muchuweti, 2006), these results proved that the extracts from S. rebaudiana leaf possess significant antioxidant properties. For these extracts and this oil, the medicinal benefit derived from their use may include prevention of oxidative skin damage and subsequent disease progression.…”

Section: Antioxidant Activity Analysissupporting

confidence: 48%

Study on chemical composition and biological activities of essential oil and extracts from Stevia rebaudiana Bertoni leaves

Muanda¹,

Soulimani

Diop³

et al. 2011

LWT - Food Science and Technology

128

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Section: Antioxidant Activity Analysissupporting

confidence: 48%

Study on chemical composition and biological activities of essential oil and extracts from Stevia rebaudiana Bertoni leaves

Muanda¹,

Soulimani

Diop³

et al. 2011

LWT - Food Science and Technology

128

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“…hybridus has great potential for the treatment of coliform urinary tract infection as indicated by the current study. Chitindingu et al (2007) isolated antioxidant and phenolic substances from A. hybridus which are known to have anti-human immunodeficiency virus (HIV) properties. Thus the use of this leafy vegetable is recommended for combating opportunistic related infections in HIV/AIDS patients.…”

Section: Resultsmentioning

confidence: 99%

Screening of some kenyan medicinal plants for antibacterial activity

Wagate

Mbaria

Gakuya

et al. 2009

Phytotherapy Research

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Eleven medicinal plants used by traditional healers in Machakos and Kitui District were screened, namely: Ajuga remota Benth, Aloe secundiflora Engl, Amaranthus hybridus L, Cassia didymobotrya Fes, Croton macrostachyus Del, Entada leptostachya Harms, Erythrina abyssinica DC, Harrisonia abyssinica Oliv, Schkuhria pinnata O. Ktze, Terminalia kilimandscharica Engl and Ziziphus abyssinica Hochst for potential antibacterial activity against four medically important bacterial strains, namely: Bacillus cereus ATCC 11778, Escherichia coli ATCC 25922, Micrococcus lutea ATCC 9341 and Pseudomonas aeruginosa ATCC 27853. The antibacterial activity of methanol extracts was determined as the minimum inhibitory concentration (MIC). The plant extracts were more active against Gram-positive (G+) than Gram-negative (G-) bacteria. The positive controls were streptomycin and benzylpenicillin for G- and G+ bacteria, respectively, both had a significant MIC at <1 mg/mL. The most susceptible bacteria were B. cereus, followed by M. lutea, while the most resistant bacteria were Ps. aeruginosa, followed by E. coli. The present study supports the use of these plants by the herbalists in the management of bacterial ailments. H. abyssinica and T. kilimandscharica showed the best antibacterial activity; hence these plants can be further subjected to phytochemical and pharmacological evaluation.

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“…Combrestatins and flavonoids have been isolated from Terminalia sp. (Garcez et al 2006), terpenoids, glycosides, ajugarin I and II have been isolated from the Lamiaceae family (Matu & van Staden 2003, Manguro et al 2006), antioxidants and phenols from A. remota (Chitindingu et al 2007), an antifungal thaumatin-like protein from Cassia didymobotrya (Vitali et al 2006) and saponins isolated from E. leptostachya (Ka-reru et al 2008).…”

Section: Resultsmentioning

confidence: 99%

Antibacterial and cytotoxic activity of Kenyan medicinal plants

Cyrus¹,

Daniel

Nanyingi³

et al. 2008

Mem. Inst. Oswaldo Cruz

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(Miaron et al. 2004, Kareru et al. 2007, Njoroge & Bussman 2007. The high cost of imported conventional drugs and/or inaccessibility to western health care facilities has led to overreliance on traditional medicine since it is affordable and available to rural people. On the other hand, even when western health facilities are available, traditional medicine is viewed as an efficient and an acceptable system from a cultural perspective (Munguti 1997, Miaron et al. 2004.Infections associated with bacterial pathogens are among some of the indications treated using traditional remedies in Kenya (Njoroge & Bussman 2007). Bacterial infections are prevalent due to various factors such as the HIV/AIDS pandemic, poor hygiene, overcrowding and resistance to convectional antimicrobials. Natural products of higher plants may provide a new source of antimicrobial agents with possibly novel mechanisms of action (Adenisa et al. 2000).The aim of this study was to screen methanolic medicinal plant extracts traditionally used for the management of infectious diseases in Kenya. Brine shrimp (Artemia salina Leach) lethality test (BSLA) was used to systematically evaluate the cytotoxic effects of extracts. Broth dilution assays using Gram-negative bacteria Escherichia coli (ATCC 25922) and Pseudomonas aerugenosa (ATCC 27853) and Gram-positive bacteria Staphylococcus aureus (ATCC25923) and Bacillus cereus (ATCC 11778) was utilized to obtain the minimal inhibitory concentrations (MIC) of the plant extracts. MATERIALS AND METHODSPlant materials -Plants were collected during dry season from January-March 2006 in Machakos and Kitui areas of the Eastern province, Kenya, based on ethnopharmacological use through interviews with traditional health practitioners. The plants were identified by Mr. Ochung, a plant taxonomist, and voucher specimens (Table I) were deposited at the Department of Land Resource Management and Agricultural Technology Herbarium, University of Nairobi.Extraction -The plant parts (whole plant, bark, root, leaves, tubers or a mixture) were chopped into small pieces, air dried at rt (25°C) under shade and pulverized using a laboratory mill yielding 300-400 g. The fine powders were separately soaked in 70% methanol (3 × 500 mL) for four days at rt to produce extracts. The extracts were filtered and concentrated using rota vapor at 50°C and 100 mbar. Further preparation was done according to Gebre-Mariam et al. (2006). The lyophilized extracts were kept at +4°C until they were screened. The yields of the methanol extracts were between 5%-8.4%. The methanolic extract yields were obtained as follows: leaves of Ajuga remota Benth (320 g) yielded 7.5%, leaves of Amaranthus hybridus L. (350 g) yielded 4.2%, leaves of Cassia didymobotrya Fres. (320 g) yielded 8.4%, a mixture of leaves and roots of Croton macrostachyus Del. (400 g) yielded 5.2%, tubers of Entada leptostachya Harms (300 g) yielded 6%, mixture of leaves and bark of Harrisonia abyssinica Oliv (360 g) yielded 6.5% and bark of Terminalia kilimandscharica Engl. (370...

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Phenolic Compound Content, Profiles and Antioxidant Activities of Amaranthus Hybridus (Pigweed), Brachiaria Brizantha (Upright Brachiaria) and Panicum Maximum (Guinea Grass)

Cited by 29 publications

References 17 publications

Study on chemical composition and biological activities of essential oil and extracts from Stevia rebaudiana Bertoni leaves

Study on chemical composition and biological activities of essential oil and extracts from Stevia rebaudiana Bertoni leaves

Screening of some kenyan medicinal plants for antibacterial activity

Antibacterial and cytotoxic activity of Kenyan medicinal plants

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