[(PhCH2O)2P(CH3)2CHNCH(CH3)2]2PdCl2/CuI as Cocatalyst for Coupling-Cyclization of 2-Iodophenol with Terminal Alkynes in Water

Jiang, Panli; Guo, Mengping; Fu, Leiqing; Wen, Yuh‐Sheng; Shen, Xiuli; Zhou, Lanjiang

doi:10.3390/catal8040136

Cited by 8 publications

(2 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…2-substituted benzo[b]furans/furo-pyridines are important building blocks in biologically active compounds such as anti-inflammation agents and anti-fungal activities (Scheme 1) [1][2][3][4][5][6]. Due to these excellent properties, the synthesis of these skeletons has become a hot spot in recent years [7,8]. Recently, York, Panli, and co-workers showed the coupling of unsaturated hydrocarbons with heteroaryl and aryl compounds using Pd catalysis [8,9].…”

Section: Introductionmentioning

confidence: 99%

“…Due to these excellent properties, the synthesis of these skeletons has become a hot spot in recent years [7,8]. Recently, York, Panli, and co-workers showed the coupling of unsaturated hydrocarbons with heteroaryl and aryl compounds using Pd catalysis [8,9]. Following their work, several methods were developed to synthesize 2-substituted benzo[b]furan/furo-pyridines [10][11][12][13].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Synthesis of 2-Substituted Benzo[b]furans/furo-Pyridines Catalyzed by NiCl2

2019

View full text Add to dashboard Cite

The first Ni-catalyzed tandem synthesis of 2-substituted benzo[b]furans/furo-pyridines from 2-halophenols and 1-alkynes was explored under Cu-free and phosphine-free conditions. The protocol was carried out with NiCl2/5-nitro-1, 10-phenanthroline in DMA (N,N-dimethylacetamide) at 120 °C. It was found to be simple, cost effective, and have a wide substrate scope. Additionally, the method is compatible with heteroaryl substrates, resulting in the formation of 2-substituted benzo[b]furans/furo-pyridines in reasonable to good yields.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Synthesis of 2-Substituted Benzo[b]furans/furo-Pyridines Catalyzed by NiCl2

2019

View full text Add to dashboard Cite

show abstract

Novel self‐doped Pd/Cu bimetals in CMC/PANI composites: Efficient heterogeneous catalyst for cooperative Sonogashira and Sonogashira‐cyclization tandem reactions

Huang,

Lin,

et al. 2024

Applied Organom Chemis

View full text Add to dashboard Cite

A new Pd/Cu bimetal catalyst supported on carboxymethylcellulose/polyaniline (CMC/PANI) composites (Pd/Cu@CMC/PANI) was fabricated to investigate the cooperative effect between Pd/Cu bimetals in Sonogashira reactions. This approach involves the self‐organization of aniline on CMC via H‐bond, enabling in situ oxidative polymerization using Pd(II) and Cu(II) ions as co‐oxidants. Subsequently, Pd and Cu are self‐deposited on the resulting CMC/PANI composites through the interaction of coordination and metathesis. The morphological and compositional analysis of the prepared catalyst was performed using various analytical tools such as ICP‐AES, FT‐IR, XPS, SEM, TEM, EDS, elemental mapping, and TGA. The Pd/Cu@CMC/PANI composite as a cooperative catalyst for the Sonogashira couplings exhibited high catalytic activity with relatively low Pd loading over its monometallic Pd counterpart, demonstrating the cooperative effect between Pd and Cu. Then, this bimetallic catalyst was successfully adapted for Sonogashira‐cyclization tandem reaction for the synthesis of benzofuran with excellent yields. Significantly, the Pd/Cu@CMC/PANI catalyst exhibited thermal stability under the reaction conditions and could be easily retrieved and reused repeatedly for five runs in the model reaction without significant discernible performance degradation.

show abstract

Five-Membered Ring Systems: Furans and Benzofurans

Kwiecień

Wodnicka

2020

Progress in Heterocyclic Chemistry

View full text Add to dashboard Cite

[(PhCH2O)2P(CH3)2CHNCH(CH3)2]2PdCl2/CuI as Cocatalyst for Coupling-Cyclization of 2-Iodophenol with Terminal Alkynes in Water

Cited by 8 publications

References 26 publications

Synthesis of 2-Substituted Benzo[b]furans/furo-Pyridines Catalyzed by NiCl2

Synthesis of 2-Substituted Benzo[b]furans/furo-Pyridines Catalyzed by NiCl2

Novel self‐doped Pd/Cu bimetals in CMC/PANI composites: Efficient heterogeneous catalyst for cooperative Sonogashira and Sonogashira‐cyclization tandem reactions

Five-Membered Ring Systems: Furans and Benzofurans

Contact Info

Product

Resources

About