Phase transitions in cholesterol crystallized from various solvents

Extraction of cholesterol from cattle brain using supercritical carbon dioxide

“…corresponding enthalpies between 3.71 and 6.84 kcal/mole. The crystal-crystal transitions and melting transition and respective enthalpy changes were comparable with the data-reported values [43]. The lower melting temperature for cholesterol extracted by SC CO 2 method may be attributed to low purity of the sample as indicated by GC.…”

Growth and micro-topographical studies of gel grown cholesterol crystals

“…The solubility of cholesterol in various solvents has been widely studied and reported (Bar et al 1984;Pal and Moulik 1987). Cholesterol was crystallized from different solvents under various conditions and the effect of solvents on the crystal structure was studied (Garti et al 1980(Garti et al , 1981. Gel is an ideal medium to grow biological crystals since its structure is similar to the mucus in the living organisms.…”

Phase Transition and Crystal Structure of the 37°C Form of Cholesterol

“…The calorimetric and NMR data have been taken to indicate that the phase transition involves a change in the packing of the side chain methyl groups (2) or other rearrangement or onset of disorder in the side chains (7,8). The strong influence of cholesterol content on the gel-liquid crystal phase transitions of lipid bilayers and membranes has been qualitatively ascribed to the lateral packing requirements of rigid steroid skele-tons and flexible hydrocarbon chains (9)(10)(11)(12).…”

“…Spleen necrosis virus is an avian retrovirus that is highly pathogenic in vivo (7). In cell culture SNV causes cell death during acute infection (8), although some cells survive and multiply while continuing to produce virus (9).…”