Abstract:After potentially curative treatment, colorectal cancer (CRC) patients remain at high risk for recurrence, second primary CRC, and high-risk adenomas. In combination with existing data, our previous findings provide a rationale for reducing tissue polyamines as tertiary prevention in non-metastatic CRC patients. The goal of this study was to demonstrate rectal tissue polyamine reduction in optimally treated stage I-III CRC patients after intervention with daily oral aspirin + dietary arginine restriction. A si… Show more
“…Additionally, this collection features studies that emphasize the beneficial role of Selective Serotonin Reuptake Inhibitors, Non-Steroidal Anti-Inflammatory Drugs, and aspirin in reducing colorectal cancer risk [ 8 , 9 , 10 ]. Despite the importance of these modifiable factors, colorectal cancer risk is also increased in patients affected by Inflammatory Bowel Diseases [ 11 ].…”
Gastrointestinal tract cancers, including oral, oesophageal, stomach, liver, pancreas, and colorectal cancers, represent a significant worldwide health concern [...]
“…Additionally, this collection features studies that emphasize the beneficial role of Selective Serotonin Reuptake Inhibitors, Non-Steroidal Anti-Inflammatory Drugs, and aspirin in reducing colorectal cancer risk [ 8 , 9 , 10 ]. Despite the importance of these modifiable factors, colorectal cancer risk is also increased in patients affected by Inflammatory Bowel Diseases [ 11 ].…”
Gastrointestinal tract cancers, including oral, oesophageal, stomach, liver, pancreas, and colorectal cancers, represent a significant worldwide health concern [...]
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.