Gastrointestinal Tract Cancers, an Increasing Burden of the Modern Era: Epidemiology and Prevention

Abstract

Gastrointestinal tract cancers, including oral, oesophageal, stomach, liver, pancreas, and colorectal cancers, represent a significant worldwide health concern [...]

Prospects of liquid biopsy in the prognosis and clinical management of gastrointestinal cancers

“…Gastrointestinal (GI) cancers, encompassing colorectal, stomach, esophageal, liver, and pancreatic cancers, exhibit varying global incidences and mortality rates ( Siegel et al, 2023a ). A recent estimate reports that gastrointestinal cancers contribute to one in three cancer incidences and one in three cancer-related deaths globally and are expected to increase in the coming years ( Sathishkumar et al, 2022 ; Kayali et al, 2023 ). Gastrointestinal tract cancers also result in the impairment of almost all quality of life (QOL) parameters, and therefore, it is essential to enhance cancer care and clinical outcomes for these cancer types ( Dalhammar et al, 2022 ; Siddiqui et al, 2023 ).…”

“…Pancreatic cancer, which is challenging to treat and frequently diagnosed at advanced stages, registers lower survival rates among gastrointestinal cancers ( Li C. et al, 2022 ). Efforts toward early detection through screenings, lifestyle modifications, and advancements in treatment remain pivotal in mitigating mortality rates across these cancers ( Kayali et al, 2023 ).…”