Pharmakognosie

Steinegger, E; Hänsel, Rudolf

doi:10.1007/978-3-662-09267-5

Cited by 26 publications

(13 citation statements)

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“…Rutaceae, Apiaceae and Asteraceae. They have a wide range of pharmacological activity, including hepatoprotective, diuretic, spasmolytic, vasodilatory and photobiological activity and inhibition of platelet aggregation [1,2]. The importance of coumarins is based not only on their medical properties; their occurrence in medicinal plants can also be used to distinguish between closely related species or to detect adulterations of plant preparations.…”

Section: Introductionmentioning

confidence: 99%

HPLC-MS and MECC analysis of coumarins

1997

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SummaryMECC separation of 11 coumarins has been achieved by use of a running electrolyte at pH 10.4 prepared from 50 mM boric acid, 10 mM sodium tetraborate and 100 mM sodium hydroxide. The buffer solution contained 50 mM SDS and, as organic modifier, 1% n-propanol. The applied voltage was 25 kV and the temperature of the capillary was kept constant at 20 ~ HPLC baseline separation of the coumarin mixture was obtained by use of a reversed-phase column and an acetonitrile-water solvent gradient. UV detection was performed at 205 nm. Peak assignment and purity control were achieved by HPLC-mass spectrometry with either an electrospray interface or an atmospheric-pressure chemical-ionization interface. Compounds were detected in either negative-or positive-ion modes. These MECC and HPLC-MS methods are suitable for 'fingerprint' analysis of a number of coumarin-containing plants, e.g. Fr. Ammi visnagae, Rd. Scopoliae and Rd. Imperatoriae.

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Section: Introductionmentioning

confidence: 99%

HPLC-MS and MECC analysis of coumarins

1997

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“…Various medicinal and pharmacological values have been observed in species of Cola (DaelsRakotoarison et al, 2003; Steinegger and Hansel, 1992). Kolanuts are often used to treat whooping cough and asthma.…”

Section: Introductionmentioning

confidence: 99%

Phytochemical and antimicrobial studies of four species of <i>Cola</i> Schott & Endl. (Sterculiaceae)

Sonibare

Soladoye

Esan

et al. 2010

Afr. J. Trad. Compl. Alt. Med.

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The in-vitro antimicrobial evaluation of ethanol extracts of four species of Cola Schott & Endl. was done using human isolated strains of Staphylococcus aureus, Staphylococcus albus, Bacillus subtilis, Klebsiella pneumonia, Pseudomonas aeruginosa, Candida albicans, Aspergillus niger as test organisms. The assays were carried out by agar well diffusion, erythromycin and ketoconazole served as the control drugs. The leaf ethanol extracts of the plants were found to be more effective against the tested fungi than the bacteria at high concentrations. None of the extracts was active against Staphylococcus aureus. Plant extract of C. acuminata (P. Beauv.) Schott & Endl. and C. nitida (Vent) Schott & Endl. showed activity on S. albus at concentrations ranging from 10-150 mgmlˉ¹ having comparable diameters of zone of inhibition of 7.3±0.03-16.0±0.0 for C. acuminata and 10.0±0.0-19.0±0.0 for C. nitida. Also, these two species of Cola demonstrated activities on C. albicans and A. niger at concentrations ranging from 90-150mgmlˉ¹ with relatively close diameters of zone of inhibition. Only C. acuminata inhibited the growth of K. pneumoniae at the MIC of 90mgmlˉ¹ whereas, C. albicans was inhibited by C. acuminata, C. millenii K. Schum and C. gigantea A.Chev. at the MIC of 120mgmlˉ¹. Phytochemical screening of the four species of Cola showed the presence of alkaloids, saponins, tannins and cardenolides in all the plants which apart from showing the probable closeness of the species could also be responsible for the observed activities. The antimicrobial property shown by the plant extracts is an evidence of the ethnomedicinal uses of the plants. The similarity observed in the phytochemical constituents and antimicrobial activities demonstrated by C nitida (Vent.) Schott & Endl., C. millenii and C.gigantea A. Chev. and C. acuminata suggest a probable closeness among these species. The results obtained in this study provide preliminary evidence of the chemotaxonomic significance of secondary metabolites and antimicrobial activities in infra-generic taxonomy of species of Cola.

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“…3,4 Sage (SalVia officinalis L.) is used extensively as a household remedy in Europe for several purposes, including to relieve inflammation of the oral cavity and throat when used as a mouthwash or gargle. 4 German health authorities have also approved its external use for digestive upset and excessive perspiration. 3,4 Sage is also used to preserve foods, especially meat and cheese, due to its antioxidant properties, as well as being employed as a spice for flavoring.…”

Section: Introductionmentioning

confidence: 99%

Bioactive Triterpenoids from Salvia Species

2006

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Salvia species are important medicinal and culinary plants, and they have been the subject of numerous chemical and biological studies. The bioactive triterpenoids of Salvia species, reported in the literature to date, are reviewed. About 200 triterpenoids, almost 80 of which are new, isolated, and characterized from about 100 Salvia species, are presented herein. In addition to the diverse biological activities of the pure triterpenoids, studies on biological activity of extracts of Salvia species are also described.

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Pharmakognosie

Cited by 26 publications

References 0 publications

HPLC-MS and MECC analysis of coumarins

HPLC-MS and MECC analysis of coumarins

Phytochemical and antimicrobial studies of four species of <i>Cola</i> Schott & Endl. (Sterculiaceae)

Bioactive Triterpenoids from Salvia Species

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