Bioactive Triterpenoids from <i>Salvia </i>Species

Topçu, Gülaçtı

doi:10.1021/np0600402

Cited by 189 publications

(122 citation statements)

References 128 publications

(165 reference statements)

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“…Two of these beverages (Samples 1 and 3) contain Anthraquinones, which possess a variety of antimicrobial, antioxidant, anti-inflammatory, antiviral, or antitumor promoting biological activities [31,32]. The presence of triterpenoids in three beverages precisely Samples 1-3 suggests the potential of the beverages exhibiting protective effects against cardiovascular disease and inflammation that are associated with this compound [33]. The intake level of the phytochemicals in the present study is low when compared with intake level of polyphenols of about 1 g in Europe [34].…”

Section: Discussionmentioning

confidence: 99%

Phytochemical Properties and Heavy Metal Contents of Commonly Consumed Alcoholic Beverages Flavouredwith Herbal Extract in Nigeria

2018

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Abstract:There is proliferation of alcoholic beverages flavoured with herbal-extracts that are perceived to have medicinal values. Information on the phytochemical and heavy metal contents of these products is scarce. This study assessed the phytochemical properties and heavy metal contents of herbal-extract flavoured alcoholic beverages in major motor parks in Ibadan, Nigeria. The phytochemical properties of the beverages were determined in triplicate using standard methods, while the heavy metal contents were assessed while using atomic absorption spectrophotometry. Data were analyzed using descriptive statistics, and means were compared using ANOVA at p < 0.05.The pH range of the beverages was 3.28-6.57 and the alcohol content was 34.0-51.5%. Detected major phytochemicals and concentration ranges were phytic acid (0.72-2.37 mg/g), alkaloids (0.42-4.11 mg/g), flavonoids (0.22-3.64 mg rutin equivalents/g), total phenols (1.13-3.66 mg gallic acid equivalents/g), anthraquinones (0.74-1.93 mg/g),and triterpenoids (0.74-1.93 mg/g). The heavy metal contents were Pb (2.13-4.70 mg/L), Cd (0.06-0.07 mg/L), Co (0.12-0.23 mg/L), Zn (0.14-0.40 mg/L), and Fe (0.72-4.22 mg/L); only Pb and Cd were above the World Health Organization (WHO) limits of 0.01 mg/L and 0.03 mg/L in water, respectively. The herbal-extract flavoured alcoholic beverages contain beneficial phytochemicals and traces of heavy metals. Safety awareness of these products for improved consumers' health would be of public health importance.

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Section: Discussionmentioning

confidence: 99%

Phytochemical Properties and Heavy Metal Contents of Commonly Consumed Alcoholic Beverages Flavouredwith Herbal Extract in Nigeria

2018

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“…Sage contains also important bioactive terpenoids such as triterpenoid ursolic and oleanolic acids [12] characterized by high lipophilicity [13]. Both components manifested hepatoprotective, anti-inflammatory, antihyperlipidemic and antitumorigenic properties [13].…”

Section: Salvia Officinalis Salvia Officinalis L (Common Sagementioning

confidence: 99%

Biological effects of four frequently used medicinal plants of Lamiaceae

Srančíková¹,

Horvathova²,

Kozics³

2014

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Cancer is one of the leading causes of death characterized by uncontrolled growth and spread of cancer cells. There are several hundred thousands of new cases of cancer worldwide. Clinical oncology is still challenged by toxicity and side effects of multimodal therapy strategies in which it is associated with poor prognosis for patients. There is an urgent necessity to develop novel therapy strategies and to utilize preventive potential of natural compounds. As the majority of anticancer drugs are of natural origin, natural products represent a valuable source for the identification and development of novel treatment options and chemopreventive mechanisms for cancer. This review is focused on the summary of published knowledges on the antioxidant and potential chemopreventive effects of biologically active substances present in the extracts of four plants of the family Lamiaceae (sage, thyme, rosemary and lavander) in different animal and in vitro systems. It is assumed that the chemopreventive and chemotherapeutic potential of natural compounds is the result of a combined action of several mechanisms.

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“…1) Several investigations showed that the chemical constituents of Salvia species were rich in triterpenoids, diterpenoids, monoterpenes and polyphenolics. [2][3][4][5] However, further chemical studies on the aerial parts of Salvia chinensis were left uncharacterized. In the course of our chemical studies on this plant, two new germacrane sesquiterpenes, salviadienol A (1) and salviadienol B (2), together with five known compounds (3)(4)(5)(6)(7) were isolated from the 70% ethanol extract of the aerial parts of Salvia chinensis.…”

Section: Notesmentioning

confidence: 99%