Pharmacovigilance in traditional chinese medicine safety surveillance

Wang, Hainan; Ye, Xiaofei; Gao, Qing-Bin; Wu, Cheng; Qian, Yuguo; Luo, Baozhang; Sun, Yongkun; He, Jia

doi:10.1002/pds.1725

Cited by 24 publications

(14 citation statements)

References 7 publications

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“…More than 9000 kinds of herbal medicines have been approved to be sold on the market [25]. There have been increasing concerns about safety and potential toxicity of herbal medicines [3,[26][27][28][29][30][31]. The development of SRS system in China has provided a new way to investigate the safety issue of herbal medicines by statistical analysis of SRS databases [32,33].…”

Section: Discussionmentioning

confidence: 99%

Detecting drug–herbal interaction using a spontaneous reporting system database: an example with benzylpenicillin and qingkailing injection

Deng

Yue

et al. 2015

Eur J Clin Pharmacol

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Section: Discussionmentioning

confidence: 99%

Detecting drug–herbal interaction using a spontaneous reporting system database: an example with benzylpenicillin and qingkailing injection

Deng

Yue

et al. 2015

Eur J Clin Pharmacol

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“…These adverse effects made its use restricted by UK Committee on Safety of Medicines (CSM) because of predisposition of adverse allergic reactions (Wang et al, 2009). …”

Section: Psoralea Fruit (Psoralea Corylifolia)mentioning

confidence: 99%

Herbal Supplements or Herbs in Heart Disease

Sharma¹

2013

Bioactive Food as Dietary Interventions for Cardiovascular Disease

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“…These adverse effects made its use restricted by UK Committee on Safety of Medicines (CSM) due to predisposition of adverse allergic reactions [30].…”

Section: Psoralea Fruit (Psoralea Corylifolia)mentioning

confidence: 99%

Recommendations on Herbs and Herbal Formula in Cancer Prevention

Sharma¹

2010

TONUTRAJ

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Herbs are naturally rich in bioactive herbiceuticals or plant products with food value to keep energy balance in the body and promise substantial therapeutic value in several diseases. Major herbs have specific active ingredient(s) with cancer therapeutic effects. Herbs are now part of nutrition supplements at nonprescription counters and their selfprescription has increased at large scale in hope of cancer prevention. The government agencies monitor and regulate the herbal use in cancer prevention and cancer management with update information of herbal side effects and safety to public. In present paper, different herbs are surveyed in the use of general health with an account of recommended potential herbs in cancer prevention. The biochemical mechanism of cancer prevention in tissues by herbs is proposed. Broadly herbs are rich in alkaloids, flavones, antioxidants, xanthones, omega-3 fatty acids, vitamins, minerals and fibers. Most of the herbs are derived from plants and they act as regulatory biochemical metabolites either by direct intermediary metabolism or regulating cancer pathways and stimulating immunity. The focus of review is to introduce available herbs, herbal biochemical action and herbiceutical anticancer formula. The herbal anticancer formula may be prepared by using: antiproliferative herb extracts combined with vitamin supplement, lactate dehydrogenase enzyme inhibitor, palliative alkalizing sodium or potassium salts as mixture in liquid, paste or syrup form. Herbiceuticals from herbs are potential anticancer supplements if used with care and regulatory guidelines.

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Pharmacovigilance in traditional chinese medicine safety surveillance

Abstract: Pharmacovigilance in TCM is still facing many challenges in playing critical roles in China. More attention should be paid to pharmacovigilance in TCM safety surveillance.

Cited by 24 publications

References 7 publications

Detecting drug–herbal interaction using a spontaneous reporting system database: an example with benzylpenicillin and qingkailing injection

Detecting drug–herbal interaction using a spontaneous reporting system database: an example with benzylpenicillin and qingkailing injection

Herbal Supplements or Herbs in Heart Disease

Recommendations on Herbs and Herbal Formula in Cancer Prevention

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