Pharmacotherapy of circulatory shock

Evaluation of gastric and bladder tonometry as indicators of tissue perfusion in induced hypotension in dogs

“…Shock is defined as a state of hemodynamic and metabolic disturbance caused by the inability of the cardiovascular system to maintain adequate tissue perfusion and delivery of oxygen (DO 2 ) and nutrients, resulting in cellular and organ dysfunction . The most common causes of imbalance between oxygen demand and delivery in dogs include hypovolemic, cardiogenic, or septic shock .…”

Septic Shock and Sepsis Syndrome in Obstetric Patients

“…Under these conditions, there is widespread peripheral vasoconstriction and reversal of the selective vasodilatory effects of lower-dose dopamine. 46 The physiologic results at high doses, all of which are countertherapeutic in septic shock patients, are diminished systemic perfusion as well as increased afterload and cardiac work. 44 Other sympathomimetic drugs that may be used in the setting of septic shock include dobutamine and norepinephrine.…”