Pharmacotherapy in the treatment of male sexual dysfunction

Rowland, David L.; Burnett, Arthur L.

doi:10.1080/00224490009552043

Cited by 18 publications

(5 citation statements)

References 109 publications

(106 reference statements)

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“…In fact, over three‐quarters of men had discussed their dysfunction with their partner, regardless of how long they had experienced the ED. The findings also indicated a general willingness for Australian men to talk to their doctor about their ED, and this likelihood increased with longer duration of ED 14 …”

Section: Discussionmentioning

confidence: 83%

“…The findings also indicated a general willingness for Australian men to talk to their doctor about their ED, and this likelihood increased with longer duration of ED. 14 However, this help-seeking behavior was least likely in men who had experienced ED for 12 months or less. The reasons most frequently cited by men who had not seen a doctor related to waiting to see if the problem would resolve on its own, and embarrassment or discomfort in raising the issue with their current doctor.…”

Section: H Matic and M P Mccabementioning

confidence: 98%

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Duration of erectile dysfunction and its relationship to treatment seeking and satisfaction with treatment using PDE5 inhibitors

Matic

McCabe

2008

Int J of Urology

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Objectives: This cross-sectional study was designed to evaluate whether the duration of erectile dysfunction (ED) influenced treatment seeking and satisfaction with treatment using PDE5 inhibitors. Methods: Participants were 409 men with ED who were primarily recruited over the internet via men's health web sites. Participants completed a questionnaire to assess the duration and perceived severity of ED, information and help-seeking behaviors for ED, and treatment usage and satisfaction with PDE5 inhibitor medication. Results:The results demonstrated that men with ED of longer duration were more likely to have discussed their ED with their partner and doctor and to have sought information and treatment for their ED problem. No differences were found in reported satisfaction with ED medication usage or expected future medication use across the varying levels of ED duration, once variance attributable to age was accounted for. Conclusions: These results suggest that men are more likely to accept that they have ED and seek treatment for their ED with increasing duration of the condition, although these men are not more satisfied with PDE5 inhibitors as a treatment option.

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Section: Discussionmentioning

confidence: 83%

Section: H Matic and M P Mccabementioning

confidence: 98%

Duration of erectile dysfunction and its relationship to treatment seeking and satisfaction with treatment using PDE5 inhibitors

Matic

McCabe

2008

Int J of Urology

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“…To treat sexual dysfunction that persists after PTSD treatment, Veterans are referred for pharmacology, couples therapy, or sex therapy [15,58]. Sex therapy [59] involves restructuring self‐defeating sexual attitudes and beliefs and modifying dysfunctional sexual behavior.…”

Section: Recommendations For Treatment and Future Researchmentioning

confidence: 99%

Sexual Dysfunction in Veterans with Post-Traumatic Stress Disorder

Tran

Dunckel

Teng

2015

The Journal of Sexual Medicine

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Introduction Veterans with post-traumatic stress disorder (PTSD) experience high rates of sexual dysfunction. However, the topic of sexual dysfunction is often overlooked clinically and underexamined in the PTSD research literature. Clinician assessment and treatment of sexual dysfunction are particularly important for Veterans, who are at increased risk of exposure to trauma. Aim Review the literature regarding sexual dysfunction among Veterans with PTSD. Method Review of the literature. Results Sexual dysfunction, including erectile difficulties in males and vaginal pain in females, is common among Veterans with PTSD. Several underlying mechanisms may account for the overlap between PTSD and sexual dysfunction. Certain barriers may contribute to the reluctance of providers in addressing problems of sexual dysfunction in Veterans with PTSD. Conclusions With the high likelihood of sexual dysfunction among Veterans with PTSD, it is important to consider the integration of treatment strategies. Efforts to further the research on this important topic are needed.

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“…The traditional functional classification of these systems (ie, a homeostatic or regulatory role for the parasympathetic component and an emergency/arousal role for the sympathetic component) does not necessarily extend to activation of the genitals. Thus, the parasympathetic and sympathetic components of the ANS both appear to contribute to sexual excitement, penile erection, and ejaculation 16,22 Stimulation of parasympathetic fibers of the pelvic nerve arising from the sacral area of the spinal cord can generate an erection. Recent studies, however, suggest a possible role for the sympathetic nervous system in erection as well, since blockage of this system produces penile engorgement and erection.…”

Section: Mechanisms Of Erection and Ejaculationmentioning

confidence: 99%

Neurobiology of Sexual Response in Men and Women

Rowland

2006

CNS Spectr.

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Sexual desire, arousal, and orgasm are mediated by complex—and as yet not fully understood—interactions of the somatic and autonomic nervous systems, operating at cerebral, spinal, and peripheral levels. Furthermore, neural activity within these systems is modulated by the presence of steroid and peptide hormones, which affect male and female response differentially. At the central level, dopaminergic and serotonergic systems appear to play a significant role in various components of sexual response, although adrenergic, cholinergic, nitergic, γ-aminobutyric acidergic, and other neuropeptide transmitter systems may contribute as well. At the peripheral level, adrenergic, cholinergic, and nitergic activation mechanisms control vascular changes that underlie vaginal lubrication and penile erection. In addition, these systems respond to descending brain and spinal influences that generate orgasmic response. Disruption of endocrine, neural, or vascular response—caused by aging, disease, surgery, or medication—has the potential to lead to sexual inadequacy. At the same time, psychological and relationship factors play an important role in healthy sexual response and may enhance or impair sexual functioning.

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Pharmacotherapy in the treatment of male sexual dysfunction

Cited by 18 publications

References 109 publications

Duration of erectile dysfunction and its relationship to treatment seeking and satisfaction with treatment using PDE5 inhibitors

Duration of erectile dysfunction and its relationship to treatment seeking and satisfaction with treatment using PDE5 inhibitors

Sexual Dysfunction in Veterans with Post-Traumatic Stress Disorder

Neurobiology of Sexual Response in Men and Women

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