Pharmacotherapy approaches to migraine prevention and treatment

Abstract

Migraine is considered one of the most important causes of disease-related disability worldwide, contributing to functional disorders as well as significant social and economic burden [1]. Although there are several medications used to treat migraine patients, many such patients either cannot tolerate the side effects or do not respond to oral migraine prevention medications. Up to 78 % of migraine patients are known to experience treatment failure [2,3].