2008
DOI: 10.1016/j.jep.2007.11.004
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Pharmacological study of antispasmodic activity of Mirabilis jalapa Linn flowers

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Cited by 17 publications
(10 citation statements)
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“…Several components such as β-sitosterol, stigmasterol, ursolic acid, oleanolic acid, brassicasterol, and Mirabilis antiviral protein, rotenoids (mirabijalone A-D, boeravinones C and F) were isolated from the aerial parts and roots of M. jalapa (Siddiqui et al, 1990, Siddqui et al, 1994Yi-Fen et al, 2002). Aoki et al (2008) and Oskay et al (2007) reported that M. jalapa had numerous biological activities such as antispasmodic, antibacterial, antiviral, antifungal and protein synthesis inhibition. M. jalapa is used in herbal medicine for the treatment of diarrhea, dysentery, conjunctivitis, edema, inflammation, swellings, muscular pain and malarial (Daniel, 2006).…”
Section: Author(s) Agree That This Article Remain Permanently Open Acmentioning
confidence: 99%
“…Several components such as β-sitosterol, stigmasterol, ursolic acid, oleanolic acid, brassicasterol, and Mirabilis antiviral protein, rotenoids (mirabijalone A-D, boeravinones C and F) were isolated from the aerial parts and roots of M. jalapa (Siddiqui et al, 1990, Siddqui et al, 1994Yi-Fen et al, 2002). Aoki et al (2008) and Oskay et al (2007) reported that M. jalapa had numerous biological activities such as antispasmodic, antibacterial, antiviral, antifungal and protein synthesis inhibition. M. jalapa is used in herbal medicine for the treatment of diarrhea, dysentery, conjunctivitis, edema, inflammation, swellings, muscular pain and malarial (Daniel, 2006).…”
Section: Author(s) Agree That This Article Remain Permanently Open Acmentioning
confidence: 99%
“…Moreover, methanolic extracts from the flowers, stems and leaves induced contractions of isolated jejunum muscle, and the most effective was the flowers extract (Cortés et al, 2004). Another recent study has shown the involvement of adrenergic and serotoninergic mechanisms in the inhibitory effect of Mirabilis jalapa flower extract on smooth muscle contractility (Aoki et al, 2008).…”
Section: Introductionmentioning
confidence: 96%
“…Dado que en los pueblos indígenas de México utilizan Mirabilis jalapa para curar muchas enfermedades, incluyendo la disentería, diarrea, dolor muscular y cólico abdominal. Se han hecho estudios con esta planta medicinal, en especial las flores, teniendo acción antiespasmódica (Aoki, 2008). Mirabilis jalapa es una planta muy corriente en terrenos yermos cerca de los bosques y en patios y jardines.…”
Section: Introductionunclassified
“…Mirabilis jalapa también se le conoce con los siguientes nombres comunes en todo el mundo: "Buenas tardes", "Don diego de noche", "Don pedros", "Periquitos", "Maravilla" o "Clavelina" (OMS, 2013). Existe bibliografía que hace mención al uso que tienen las plantas con efectos antiespasmódicos o relajantes, Aoki K. et al en la ciudad de México en el año 2008 realizó un trabajo sobre el "Estudio farmacológico de la actividad antiespasmódica de flores Mirabilis jalapa Linn", donde caracterizó algunas propiedades farmacológicas del extracto de flores de Mirabilis jalapa; el estudio concluyó que extracto de Mirabilis jalapa pueden implicar un mecanismo serotoninérgico que, a su vez, interactúa con otros sistemas adrenérgicos (Aoki, 2008). Los radicales libres son moléculas o fragmentos de moléculas caracterizadas por tener uno o más electrones desapareados en su orbital externo, condición que los toma altamente reactivos.…”
Section: Introductionunclassified