Pharmacological safety of Plinia cauliflora (Mart.) Kausel in rabbits

Palozi, Rhanany Alan Calloi; Guarnier, Lucas Pires; Romão, Paulo Vitor Moreira; Nocchi, Samara Requena; Santos, Carlos Calixto Dos; Lourenço, Emerson Luiz Botelho; Silva, Denise Brentan; Gasparotto, Francielly Mourão

doi:10.1016/j.toxrep.2019.06.017

Cited by 11 publications

(13 citation statements)

References 57 publications

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“…The TP content ranged from 147.68 ± 2.45 to 196.63 ± 1.39 mg GAE g −1 d.w., which is higher than what has been reported in the literature. Aqueous extract of jaboticaba peels was also produced by maceration at 100 • C and pH 6 by Lequinste et al [28], who found 36.12 mg GAE g −1 d.w. Hydroethanolic extract of jaboticaba peels was produced by maceration by Meira et al [29], who obtained 47.5 mg GAE g −1 d.w. Palozi et al [30], using another extraction methodology (accelerated solvent extraction), obtained aqueous extract from jaboticaba peels with total phenolic of 181.42 ± 3.67 mg GAE g −1 d.w., which was closer to the results found in the present study. The AA of JPE was in the range of 78.61 ± 0.21% to 94.85 ± 0.09%.…”

Section: Chemical Composition and Properties Of Jpementioning

confidence: 99%

Recovery of Bioactive Compounds from Jaboticaba Peels and Application into Zein Ultrafine Fibers Produced by Electrospinning

et al. 2020

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This work focused on the recovery bioactive compounds from jaboticaba peels and to develop ultrafine fibers from zein incorporated with the jaboticaba extract by electrospinning technique. Jaboticaba peel extracts (JPE) were obtained by maceration according a central composite rotational design (CCDR) and characterized with respect to total phenolic content (TP), antioxidant activity (AA) and total anthocyanin (TA). The optimal condition for the extraction was obtained using a desirability function in order to maximize the presence of bioactive compounds. Under these conditions the amount of cyanidin-3-glucoside (Cn-3-Glu) and the antimicrobial inhibition (AI) of E. coli were evaluated. Ultrafine fibers were obtained by electrospinning technique using zein in an aqueous ethanol as solvent and freeze-dried JPE at different concentrations (1.7% and 3.3%) to produce a composite membrane. The apparent viscosity and electrical conductivity of the polymer solutions, as well as the morphology, thermal stability and functional groups of the ultrafine fibers, were evaluated. The optimal conditions for extraction were 88 °C and pH 1. Under these conditions, a high amount of Cn-3-Glu was obtained (718.12 mg 100 g−1), along with 22.2% antimicrobial inhibition against E. coli. The addition of JPE into composite membranes did not affect the morphology of fibers, which presented a homogeneous and continuous format. Therefore, fibers containing JPE showed interesting characteristics for the food packaging industry.

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Section: Chemical Composition and Properties Of Jpementioning

confidence: 99%

Recovery of Bioactive Compounds from Jaboticaba Peels and Application into Zein Ultrafine Fibers Produced by Electrospinning

et al. 2020

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“…In vivo studies were performed by Batista et al [141], who obtained an improvement in the triglyceride excretion and hepatic lipid peroxidation in rats fed a high-fat diet enriched with lyophilized jabuticaba peel. Palozi et al [142] showed that the oral use of ethanolic extracts of jabuticaba peel in rabbits did not cause significant changes in respiratory, cardiovascular, and central nervous system functions, ensuring pharmacological safety for the use of this residue. However, biological studies of jabuticaba seeds are scarce, and further research is required to assure the complete safety of these potential sources of bioactive compounds.…”

Section: Fruit By-products (Seeds): Chemical Characterization and mentioning

confidence: 99%

Fruit Seeds as Sources of Bioactive Compounds: Sustainable Production of High Value-Added Ingredients from By-Products within Circular Economy

et al. 2019

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The circular economy is an umbrella concept that applies different mechanisms aiming to minimize waste generation, thus decoupling economic growth from natural resources. Each year, an estimated one-third of all food produced is wasted; this is equivalent to 1.3 billion tons of food, which is worth around US$1 trillion or even $2.6 trillion when social and economic costs are included. In the fruit and vegetable sector, 45% of the total produced amount is lost in the production (post-harvest, processing, and distribution) and consumption chains. Therefore, it is necessary to find new technological and environmentally friendly solutions to utilize fruit wastes as new raw materials to develop and scale up the production of high value-added products and ingredients. Considering that the production and consumption of fruits has increased in the last years and following the need to find the sustainable use of different fruit side streams, this work aimed to describe the chemical composition and bioactivity of different fruit seeds consumed worldwide. A comprehensive focus is given on the extraction techniques of water-soluble and lipophilic compounds and in vitro/in vivo functionalities, and the link between chemical composition and observed activity is holistically explained.

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“…Moreover, the industrial process of this fruit generates by-products, such as peels and seeds, which have a higher phenolic content than the pulp and are normally discarded in the environment [5]. Although the peels are considered a residue, their extracts highlight their antioxidant, anti-inflammatory, and antimicrobial properties [7]. This suggests that the peel presents itself as a potential and sustainable alternative to the use of synthetic additives.…”

Section: Introductionmentioning

confidence: 99%

Promising New Material for Food Packaging: An Active and Intelligent Carrageenan Film with Natural Jaboticaba Additive

Barreto

Moraes

Morais

et al. 2022

Foods

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This research focused on the development of active and intelligent films based on a carrageenan biopolymer incorporated with jaboticaba peels extract (JPE). The bioactive extract was obtained by maceration extraction and showed high concentrations of total phenolic content (TP), total anthocyanin (TA), cyanidin-3-glucoside (Cn-3-Glu), antioxidant activity (AA), and microbial inhibition (MI) against E. coli, being promising for use as a natural additive in food packaging. The carrageenan films were produced using the casting technique, incorporating different concentrations of JPE, and characterized. The results of the thickness and Young’s modulus of the film increased in the films supplemented with JPE and the addition of the extract showed a decrease in elongation capacity and tensile strength, in water vapor permeability, and a lower rate of swelling in the water. In addition, the incorporation of JPE into the polymeric matrix promotes a change in the color of the films when compared to the control film and improves the opacity property. This is a positive effect as the material has a UV-vis light barrier which is interesting for food packaging. The increase in the active potential of the films was directly proportional to the concentration of JPE. The films results showed visible changes from purple to brown when in contact with different pH, which means that films have an intelligent potential. Accordingly, this novel carrageenan based-film incorporated with JPE could be a great strategy to add natural additives into packaging material to obtain an active potential and also an indicator for monitoring food in intelligent packaging.

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Pharmacological safety of Plinia cauliflora (Mart.) Kausel in rabbits

Abstract: Graphical abstract

Cited by 11 publications

References 57 publications

Recovery of Bioactive Compounds from Jaboticaba Peels and Application into Zein Ultrafine Fibers Produced by Electrospinning

Recovery of Bioactive Compounds from Jaboticaba Peels and Application into Zein Ultrafine Fibers Produced by Electrospinning

Fruit Seeds as Sources of Bioactive Compounds: Sustainable Production of High Value-Added Ingredients from By-Products within Circular Economy

Promising New Material for Food Packaging: An Active and Intelligent Carrageenan Film with Natural Jaboticaba Additive

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