1991
DOI: 10.2165/00003088-199121050-00007
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Pharmacokinetics of Theophylline and its Metabolites During Acute Renal Failure

Abstract: After unsuccessful therapy with salbutamol syrup and inhaled terbutaline a 3-year-old boy with an acute exacerbation of asthma was treated with nebulised salbutamol (albuterol), intravenous aminophylline and hydrocortisone. His condition continued to deteriorate and he required artificial ventilation. Subsequently, he became anuric, with liver dysfunction, nonspecific encephalopathy and limb tremor. Peritoneal dialysis was started. Plasma theophylline concentrations were monitored and maintained in the therape… Show more

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Cited by 17 publications
(2 citation statements)
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References 21 publications
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“…Cigarettes, inhalers, and tea were associated with higher spiral scores in our regression model. Nicotine, in cigarettes, is well known to exacerbate tremor,3, 29 as are caffeine30 and methylxanthines,31 in tea. Similarly, asthma inhalers are well known to exacerbate tremor 32.…”
Section: Discussionmentioning
confidence: 99%
“…Cigarettes, inhalers, and tea were associated with higher spiral scores in our regression model. Nicotine, in cigarettes, is well known to exacerbate tremor,3, 29 as are caffeine30 and methylxanthines,31 in tea. Similarly, asthma inhalers are well known to exacerbate tremor 32.…”
Section: Discussionmentioning
confidence: 99%
“…The successful experience of Peyriere et al [2] was therefore unique and worth further study. However, we would caution the use of aminophylline under such circumstances especially in the presence of renal impairment [4].…”
mentioning
confidence: 99%