Pharmacognostic and Phytochemical studies on Leptadenia reticulata (retz.) wight &amp; arn. and Ichnocarpus frutescens r. br. for identification of distinguishing biomarkers

Mammen, Denni; Daniel, M; Sane, R. T.

doi:10.1016/s0975-3575(11)80019-2

Cited by 7 publications

(11 citation statements)

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“…In India, it is mainly found in Rajasthan, Gujarat, Punjab, the Himalayan ranges, Khasi Hills, Sikkim, Deccan Plateau, Konkan ranges, Karnataka, and Kerala up to an altitude of 2000 m [ 25 , 27 ]. Apart from India, it is also reported to be distributed in the tropical and subtropical parts of Africa, Burma, Nepal, Sri Lanka, Malay Peninsula, Cambodia, the Philippines, Mauritius, and Madagascar [ 20 , 22 , 28 ]. People in Gujarat and Kathiawar use this plant as a pot herb [ 22 ].…”

Section: Botanical Aspects Of L Reticulatamentioning

confidence: 99%

“…In spite of intensive conventional research effort and vast agronomic practices, the desired L. reticulata production target has not been achieved thus far. L. reticulata is often adulterated with many other herbs, including Holostemma ada-kodien , Dendrobium ovatum , D. macraei , Flickingeria macraei , Cimicifuga foetida , and Ichnocarpus frutescens [ 20 , 21 , 22 , 23 ]. Thus, the authenticity of L. reticulata is another great challenge in the herbal medicine industry.…”

Section: Introductionmentioning

confidence: 99%

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Leptadenia reticulata (Retz.) Wight & Arn. (Jivanti): Botanical, Agronomical, Phytochemical, Pharmacological, and Biotechnological Aspects

et al. 2017

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Leptadenia reticulata (Retz.) Wight & Arn. (Apocynaceae), is a traditional medicinal plant species widely used to treat various ailments such as tuberculosis, hematopoiesis, emaciation, cough, dyspnea, fever, burning sensation, night blindness, cancer, and dysentery. In Ayurveda, it is known for its revitalizing, rejuvenating, and lactogenic properties. This plant is one of the major ingredients in many commercial herbal formulations, including Speman, Envirocare, Calshakti, Antisept, and Chyawanprash. The therapeutic potential of this herb is because of the presence of diverse bioactive compounds such as α-amyrin, β-amyrin, ferulic acid, luteolin, diosmetin, rutin, β-sitosterol, stigmasterol, hentricontanol, a triterpene alcohol simiarenol, apigenin, reticulin, deniculatin, and leptaculatin. However, most biological studies on L. reticulata are restricted to crude extracts, and many biologically active compounds are yet to be identified in order to base the traditional uses of L. reticulata on evidence-based data. At present, L. reticulata is a threatened endangered plant because of overexploitation, unscientific harvesting, and habitat loss. The increased demand from pharmaceutical, nutraceutical, and veterinary industries has prompted its large-scale propagation. However, its commercial cultivation is hampered because of the non-availability of genuine planting material and the lack of knowledge about its agronomical practices. In this regard, micropropagation techniques will be useful to obtain true-to-type L. reticulata planting materials from an elite germplasm to meet the current demand. Adopting other biotechnological approaches such as synthetic seed technology, cryopreservation, cell culture, and genetic transformation can help conservation as well as increased metabolite production from L. reticulata. The present review summarizes scientific information on the botanical, agronomical, phytochemical, pharmacological, and biotechnological aspects of L. reticulata. This comprehensive information will certainly allow better utilization of this industrially important herb towards the discovery of lead drug molecules.

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Section: Botanical Aspects Of L Reticulatamentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Leptadenia reticulata (Retz.) Wight & Arn. (Jivanti): Botanical, Agronomical, Phytochemical, Pharmacological, and Biotechnological Aspects

et al. 2017

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“…In India, it is mainly found in Rajasthan, Gujarat, Punjab, the Himalayan ranges, Khasi Hills, Sikkim, Deccan Plateau, Konkan ranges, Karnataka, and Kerala up to an altitude of 2000 m [27,29]. Apart from India, it is also reported to be distributed in the tropical and subtropical parts of Africa, Burma, Nepal, Sri Lanka, Malay Peninsula, Cambodia, the Philippines, Mauritius, and Madagascar [22,24,30,31]. People in Gujarat and Kathiawar use this plant as a pot herb.…”

Section: Origin and Distributionmentioning

confidence: 99%

“…Stem is yellowish white in color with longitudinal lenticels [27]. Mammen et al [24] reported that the lower epidermis of the leaf contain anisocytic stomata, and the presence of multicellular, uniseriate, and smooth trichomes are the striking features offor identifying adulteration in L. reticulata. The epidermal layer of the leaf is composed of rectangular cells, and mesophyll consists of 3-4 layers of palisade and spongy parenchymal layers [37].…”

Section: Morphologymentioning

confidence: 99%

“…They used HPTLC to detect β-carotene from the aerial parts of the plant extracts. Likewise, Mammen et al, [24] conducted the biomarker study to distinguish L. reticulata from another morphologically similar plant Ichnocarpus frutescens to detect adulteration. Likewise, a HPTLC method to validate the occurrence of four compounds, namely alpha-amyrin, beta-sitosterol, lupeol, and n-triacontane from L. reticulata [31].…”

Section: Adulteration and Authentication Of L Reticulatamentioning

confidence: 99%

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<em>Leptadenia reticulata</em> (Retz.) Wight (Jivanti): Botanical, Agronomical, Phytochemical, Pharmacological, and Biotechnological Aspects

Mohanty¹,

Swamy²,

Sinniah³

et al. 2017

Preprint

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Leptadenia reticulata (Ritz.) Wight (Asclepiadaceae), a traditional medicinal plant species, is widely used in traditional medicine to treat various ailments such as tuberculosis, hematopoiesis, emaciation, cough, dyspnea, fever, burning sensation, night blindness, cancer, and dysentery. In Ayurveda, it is known for its revitalizing, rejuvenating, and lactogenic properties. This plant is one of the major ingredients in many commercial herbal formulations, including Speman, Envirocare, Calshakti, Antisept, and Chyawanprash. The therapeutic potential of this herb is because of the presence of diverse bioactive compounds such as α-amyrin, β-amyrin, ferulic acid, luteolin, diosmetin, rutin, β-sitosterol, stigmasterol, hentriacontanol, a triterpene alcohol simiarenol, apigenin, reticulin, deniculatin, and leptaculatin. However, most biological studies on L. reticulata are restricted to crude extracts, and many biologically active compounds are yet to be identified in order to claim the traditional uses of L. reticulata into evidence-based uses. At present, L. reticulata is a threatened endangered plant because of overexploitation, unscientific harvesting, and habitat loss. The increased demand from pharmaceutical, nutraceutical, and veterinary industries has prompted its large-scale propagation. However, its commercial cultivation is hampered because of the non-availability of genuine planting material and the lack of knowledge on its agronomical practices. In this regard, micropropagation technique will be useful to obtain true-to-type L. reticulata planting materials from an elite germplasm to meet the current demand. Adopting other biotechnological approaches such as synthetic seed technology, cryopreservation, cell culture, and genetic transformation can warrant conservation as well as increased metabolite production from L. reticulata. The present review summarizes scientific information on the botanical, agronomical, phytochemical, pharmacological, and biotechnological aspects of L. reticulata. This comprehensive information will certainly allow better utilization of this industrially important herb towards the discovery of lead drug molecules.

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Somatic embryogenesis in Leptadenia reticulata (Retz.) Wight and Arn along with assessment of shoot and callus cultures for HPTLC fingerprint and quantification of p-coumaric acid

Patel

Joshi

Pathak

et al. 2021

Plant Cell Tiss Organ Cult

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Pharmacognostic and Phytochemical studies on Leptadenia reticulata (retz.) wight & arn. and Ichnocarpus frutescens r. br. for identification of distinguishing biomarkers

Cited by 7 publications

References 0 publications

Leptadenia reticulata (Retz.) Wight & Arn. (Jivanti): Botanical, Agronomical, Phytochemical, Pharmacological, and Biotechnological Aspects

Leptadenia reticulata (Retz.) Wight & Arn. (Jivanti): Botanical, Agronomical, Phytochemical, Pharmacological, and Biotechnological Aspects

<em>Leptadenia reticulata</em> (Retz.) Wight (Jivanti): Botanical, Agronomical, Phytochemical, Pharmacological, and Biotechnological Aspects

Somatic embryogenesis in Leptadenia reticulata (Retz.) Wight and Arn along with assessment of shoot and callus cultures for HPTLC fingerprint and quantification of p-coumaric acid

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