Pharmacognostic and Phytochemical Investigation of Ailanthus Excelsa Roxb. Bark

Bhalke, R. D.; Giri, Mahendra

doi:10.22159/ajpcr.2020.v13i3.36409

Cited by 3 publications

(2 citation statements)

References 11 publications

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“…Leaves are nearly orbicular or oblong, sometimes ± lobed, 24-34 × 14-29 cm, leathery, abaxially densely yellowish and gray stellate velutinous, adaxially hairy or glabrous. Base is cordate with entire crenate margin, truncate apex, nearly rounded, or pointed [11,12] .…”

Section: Macroscopic Studiesmentioning

confidence: 99%

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a

Jena¹,

Verma²,

Kumar³

et al. 2023

J Pharmacogn Phytochem

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Herbal medicines are the synthesis of therapeutic experiences of generations of practicing physicians of indigenous systems of medicine for over hundreds of years. Herbs have stood the test of time for their safety, efficacy, cultural acceptability and lesser side effects. Pterospermum acerifolium Linn is a medicinal herb commonly known as kanakchampa belongs to family Sterculiaceae, which has since long been used in traditional system of medicine for its magical effects to cure various diseases. Traditionally the plant is used as a general tonic, anti tumor agent, analgesic and for the treatment of diabetes, gastrointestinal disorders, leprosy, blood troubles, bronchitis, cough, cephalic pain, migraine and inflammation, small pox and also haemostatic and antimicrobial agent etc. whereas the plant possess beneficial effects such as anti-oxidant, Antinociceptive, antiulcer, hepatoprotective, anti inflammatory, antimicrobial, wound healing, Antimitotic and anticancer activity, Immunosuppressive activity, Anthelmintic activity, Antihyperlipidimic activity and osteogenic activity and many other medicinal properties. This activity of the plant possess due to the important phytochemical constituents like amino acids, sugars, alkaloids, glycosides, tannins, triterpenoids, carbohydrates and flavonoids etc. This review article attempts to highlight the available literature on Pterospermum acerifolium with respect to its ethnomedicinal and traditional uses, chemical constituents and summary of its various pharmacologic activities and clinical effects which will helpful to create interest towards future research work and may be useful in developing new formulations with more therapeutic and economical value.

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Section: Macroscopic Studiesmentioning

confidence: 99%

“…Powder characters showed presence of lignified fibers, calcium oxalate crystals, starch grains and vessel. The total ash, acid insoluble ash and water-soluble ash values were observed to be 3.3%, 1.9% and 1.1% respectively [11,12] .…”

Section: Microscopical Studiesmentioning

confidence: 99%

a

Jena¹,

Verma²,

Kumar³

et al. 2023

J Pharmacogn Phytochem

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Examination of Phytochemical Constituents – Using Seed Extract of Madhuca Longifolia

Manikandan¹,

Parveen²,

Pa³

2020

Asian J Pharm Clin Res

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Objective: Our main scope and objective are to prepare seed extract of Madhuca longifolia, to characterize them using phytochemical activity studies, and to study the presence of so many bioactive substances established phytochemical activity and anti-foot ulcer treatment. Methods: Weighed 75 g of plant sample (without preliminary drying) accurately (precisely weighed to within 0.10 g) in a tarred evaporating dish. Care was taken so that no substantial amount of moisture is lost during preparation and that was representative of the official sample and the sample has been made to screening to following studies such as physicochemical constants, determination of moisture content, evaluation of pH of aqueous solution, evaluation of total ash, evaluation of acid-insoluble ash, evaluation of extractive values, evaluation of water-soluble extractive, evaluation of alcohol-soluble extractive, and preliminary phytochemical screening phytochemical profile of M. longifolia seed. Results: The presence of so many bioactive substances established phytochemical activity and anti-foot ulcer treatment using M. longifolia seed which supports the traditional tribal medicinal consumption of the plant. Conclusion: The quality of the plant can be estimated by determining the physical parameters. These investigations are of great importance for carrying out the revalidation and it was accomplished from the phytochemical study that the solvent extract contains flavonoid, carbohydrate, saponin, tannin, glycoside, protein, alkaloid, and amino acid which are responsible for various pharmacological actions and promotes that biological study is required to explore their potential therapeutic activities.

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Exploration of Bioactive Components of Thunbergia Coccinea, Its Pharmacognostic, Antioxidant, GCMS and Antihyperglycemic Studies

Kokila

Mahesh

Mruthunjaya

2020

Int J Pharm Pharm Sci

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Objective: An effort currently made to appraise the preliminary phytochemical, pharmacognostic criteria, antioxidant, GCMS and antihyperglycemic investigations of the Thunbergia coccinea leaves. Thunbergia coccinea (T. coccinea) is an ornamental plant considerably practiced by the tribes of forest areas of Assam (INDIA) as an analgesic, antipyretic, anti-inflammatory, antidote, hepatoprotective, antidiabetic and detoxificant substance. Methods: A comprehensive literature survey was conducted to recognize the ethnomedicinal value of T. coccinea, which is currently grown practically in all provinces. The physicochemical constants like moisture content, ash values especially total ash, insoluble acid ash, water-soluble ash and foreign organic matter were determined for the assessment of the drug. Pharmacognostic parameters like fluorescence examination and microscopic characters of the leaf were studied that would serve to verify for contamination. The extract secured by maceration was subjected to the phytochemical inquiry to determine the existence of substances and their antioxidant activity. The antihyperglycemic characteristic of alcoholic extract of the leaf was examined with the inhibition of α-amylase and α-glucosidase enzymes. Gas Chromatography-Mass Spectrometry (GCMS) studies of alcoholic extract of the plant leaf have undertaken to get an insight into the therapeutic properties of the molecules present based on online PASS prediction. Results: Various physicochemical, microscopic parameters studied gave a clear distinguishing and identifying features of T. coccinea leaf. Phytochemical screening gave an insight into the secondary metabolites existing in the plant leaf through picturizing its therapeutic properties against various ailments. Both extracts of T. coccinea leaf showed enhanced antioxidant activities. Nevertheless, the alcoholic leaf extract has shown significant antioxidant activity with an IC50 of 171.38±2.51 μg/ml and AQTC an IC50 value of 206.29±4.5 μg/ml respectively by DPPH method. Further, ACTC showed a better-reducing potential with an IC50 value of 105.74±0.61 μg/ml in comparison with AQTC IC50 value of 203.702±0.97 μg/ml by FRP method. The inhibition potentiality of α-amylase and α-glucosidase was found to be 71.66 % and 83.74 %, respectively at 500 µg/ml that rationally an adequate remedy in the treatment of type-2 diabetes. GCMS studies of the alcoholic extract unveiled the presence of different molecules like Glycerol, tris (trimethylsilyl) ether, 3,7,11,15-Tetramethyl-2-hexadecen-1-ol, Undecanoic acid, Ethyl ester, Phytol in comparison with NIST library, thereby giving its predicted therapeutic properties like sugar phosphatase inhibitor, antifungal, phobic disorders treatment, antiviral and so on. Conclusion: The selected plant had many proven therapeutic traits and, possibly, successively united on to the sort of potential therapeutic plants. Besides, isolation and discoveries will lead to the detection of certain novel compounds, which will be of potential medicinal value.

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Pharmacognostic and Phytochemical Investigation of Ailanthus Excelsa Roxb. Bark

Cited by 3 publications

References 11 publications

a

a

Examination of Phytochemical Constituents – Using Seed Extract of Madhuca Longifolia

Exploration of Bioactive Components of Thunbergia Coccinea, Its Pharmacognostic, Antioxidant, GCMS and Antihyperglycemic Studies

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