2007
DOI: 10.7326/0003-4819-146-10-200705150-00005
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Pharmacist Intervention to Improve Medication Adherence in Heart Failure

Abstract: A pharmacist intervention for outpatients with heart failure can improve adherence to cardiovascular medications and decrease health care use and costs, but the benefit probably requires constant intervention because the effect dissipates when the intervention ceases. ClinicalTrials.gov registration number: NCT00388622.

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Cited by 402 publications
(463 citation statements)
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“…[37][38][39] Of note, the MEPS prescription medication expenditures included pharmacy records which tracked both insurance and out-ofpocket expenses. Insurance type was included in the adjusted analysis; therefore, the increased costs are less likely to be due to differences in private, public, or self-insurance coverage.…”
Section: Discussionmentioning
confidence: 99%
“…[37][38][39] Of note, the MEPS prescription medication expenditures included pharmacy records which tracked both insurance and out-ofpocket expenses. Insurance type was included in the adjusted analysis; therefore, the increased costs are less likely to be due to differences in private, public, or self-insurance coverage.…”
Section: Discussionmentioning
confidence: 99%
“…Randomized controlled studies have shown that pharmacists improve medication and lifestyle adherence as part of a multidisciplinary team. [36][37][38][39][40] Some of these studies also demonstrated improvements in patients' clinical outcomes. 36,37,[39][40][41] Studies Assessing Medication Adherence A summary of studies evaluating pharmacist interventions on medication adherence is presented in Table 3.…”
Section: Pharmacist Interventions To Improve Adherencementioning
confidence: 99%
“…36,37,[39][40][41] Studies Assessing Medication Adherence A summary of studies evaluating pharmacist interventions on medication adherence is presented in Table 3. [36][37][38][39][40][41][42][43][44] One of the earliest randomized controlled trials that assessed the effect of intensive pharmacist counseling randomized 100 elderly patients with stable HF in the United Kingdom to a 3-month pharmacist counseling intervention versus standard care. 40 Medication adherence, per pill count, was 93% for the intervention group and 51% for the control group post-intervention (P < 0.001).…”
Section: Pharmacist Interventions To Improve Adherencementioning
confidence: 99%
“…Among the health literacy interventions AHRQ reviewed, those that demonstrated the potential to effectively improve health outcomes were again focused on selfmanagement and treatment adherence. 35 A closer look at the few "effective" health literacy interventions highlighted in the report reveals three randomized controlled trials [45][46][47] that tested strategies particularly well-suited for implementation within a PCMH: individualized communication, scheduled phone follow-up, and team-based care, among others ( Table 1).…”
Section: A Synergistic Approach To Cost Quality and Disparitiesmentioning
confidence: 99%
“…The difference was larger for low-literacy patients than for high-literacy patients. Patients with low literacy and other vulnerable populations are likely to benefit most from such programs Murray MD, Young J, Hoke S, et al 47 A pharmacist-led intervention for outpatients with heart failure featuring patient-centered verbal instructions and clear written instructions that made use of icons and an easy-to-follow timeline. The pharmacist worked with a multi-disciplinary team…”
Section: A Synergistic Approach To Cost Quality and Disparitiesmentioning
confidence: 99%