Phagocytosis of chemically modified carbon materials

Czajkowska, B.; Błażewicz, M.

doi:10.1016/s0142-9612(96)00103-2

Cited by 29 publications

(16 citation statements)

References 22 publications

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“…4), the penetration of the human soft tissue through the space between the carbon fibre bunches can be seen. This supports the observation previously reported by other authors, that the morphology of the surface of an implant plays an important role in the growth rate and sticking of the tissues, consequently in the integration and biocompatibility of the implant [4,6,8,9,[12][13][14][15][16][17][18][19][20][21][22][23].…”

Section: Surface Morphology Of the C/c Composite Implantsupporting

confidence: 91%

“…The composite produced is covered by pyrolytic carbon resulting from the thermo cracking of different carbonaceous materials used during the manufacturing. The biocompatibility of carbon materials, especially carbon fibres and pyrolytic carbon covered C/C composites, has been extensively studied in the last decades and they are widely accepted nowadays as biocompatible materials [3][4][5][6][7][8][9][10][11].…”

Section: Introductionmentioning

confidence: 99%

“…In case of numerous implant materials [12][13][14][15][16][17][18][19] and specifically also in case of the carbon materials [4,6,8,9,[20][21][22][23] the properties of the implant surfaces such as morphology or wettability influence the growth and adhesion of tissues and the healing of the wounds made during the surgeries.…”

Section: Introductionmentioning

confidence: 99%

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SEM and EDS investigation of a pyrolytic carbon covered C/C composite maxillofacial implant retrieved from the human body after 8 years

Sebők

Kiss

Szabó

et al. 2012

J Mater Sci: Mater Med

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The long term effect of the human body on a pyrolytic carbon covered C/C composite maxillofacial implant (CarBulat(Tm)) was investigated by comparing the structure, the surface morphology and composition of an implant retrieved after 8 years to a sterilized, but not implanted one. Although the thickness of the carbon fibres constituting the implants did not change during the 8 year period, the surface of the implant retrieved was covered with a thin surface layer not present on the unimplanted implant. The composition of this layer is identical to the composition of the underlying carbon fibres. Calcium can only be detected on the surface as a trace element implying that the new layer is not formed by bone tissue. Residual soft tissue penetrating the bulk material between the carbon fibre bunches was found on the retrieved implant indicating the importance of the surface morphology in tissue growth and adhering to implants.

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Section: Surface Morphology Of the C/c Composite Implantsupporting

confidence: 91%

Section: Introductionmentioning

confidence: 99%

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SEM and EDS investigation of a pyrolytic carbon covered C/C composite maxillofacial implant retrieved from the human body after 8 years

Sebők

Kiss

Szabó

et al. 2012

J Mater Sci: Mater Med

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“…The medical applications of carbon nanotubes are determined by the following properties: biocompatibility in contact with blood, bone, cartilage and soft tissues; biofunctionality understood as the ability of taking over certain functions of tissues by a mutual adjustment of implants and tissues properties [276][277][278].…”

Section: Carbon Nanotubesmentioning

confidence: 99%

Multifunctional Polymeric Nanostructures for Therapy and Diagnosis

Contreras-García¹,

Bucio²

2013

Nanomaterials in Drug Delivery, Imaging, and Tissue Engineering

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By definition, nanomaterials are multifunctional due to the co-incorporation of both therapeutic and bioimaging agents. Among the therapeutic applications of the polymeric nanomaterials are found drug, protein or gene delivery, tissue engineering. Other advances in bioapplications include cell-labeling, cell membrane modeling, agent delivery and targeting. Additionally, imaging nanobiotechnology is applied to sensorization and diagnosis with biosensors and biomarkers for biodetection and bioimaging, respectively. In this chapter are described the different polymeric nanostructures applied to therapy and diagnosis such as polymeric-based core-shell colloid, proteins and peptides, drug conjugates and complexes with synthetic polymers, dendrimers, vesicles, micelles, carbon nanotubes, biopolymers, smart nano polymers, metal-polymer complexes, enzyme-responsive nanoparticles, and hybrid polymeric nanomaterials. The different types of polymers are fabricated using several approaches ranging from conventional chemical methods to more sophisticated processes such as surface modification using ionizing radiation to obtain layers free of pollutants without purification and isolation processes among other advantages.

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“…Three-dimensional fibrous scaffolds made of CF, due to their excellent mechanical and electric properties, represent an attractive biomaterial, particularly in bone and cartilage regeneration [3][4][5]. Furthermore, CF can be manufactured both in the micrometer and nanometer scales which make these materials attractive for the masses as a scaffold for tissue engineering [6,7].…”

Section: Introductionmentioning

confidence: 99%