Phaeohyphomycosis in a Snow Leopard (Uncia uncia) due to Cladophialophora bantiana

Janovský, Martin; Gröne, Andrea; Ciardo, Diana; Völlm, Jörg; Burnens, A.; Fatzer, R; Bacciarini, L. N.

doi:10.1016/j.jcpa.2005.09.006

Cited by 10 publications

(8 citation statements)

References 11 publications

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“…In people, C cladosporioides occasionally infects lungs, eyes, and brain . In animals, Cladophialophora bantiana is the most frequently identified fungal agent in systemic phaeohyphomycosis . Dematiaceous fungi are reported as agents of ocular infections in dogs and cats and of dermatitis and panniculitis in dogs .…”

Section: Discussionmentioning

confidence: 99%

Cladosporium cladosporioides‐complex infection in a mixed‐breed dog

Spano

Zuliani

Peano

et al. 2018

Veterinary Clinical Pathol

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A 3-year-old female mixed-breed dog was referred with a 2-day history of serious dyspnea, coughing, lethargy, anorexia, and a low-grade right anterior lameness. At presentation, the dog had an increased respiratory rate, dull heart and lung sounds, and cyanotic mucous membranes. It was hyperthermic and slightly dehydrated. Laboratory findings showed mild neutrophilia with a left shift, while serum biochemistry variables were in the normal range. However, urinalysis revealed mild proteinuria and rare erythrocytes and leukocytes on sediment examination. Thoracic radiographs showed a diffuse mixed interstitial and alveolar pattern with an air bronchogram, while appendicular radiographs showed a right humeral interrupted brush-like periosteal reaction. Thoracic ultrasonography revealed mediastinal lymph node enlargement. Cytology from a fine-needle aspirate of mediastinal lymph nodes revealed a pyogranulomatous lymphadenitis with numerous fungal hyphae. Culture on Sabouraud dextrose agar isolated dark fungal colonies with microscopic features consistent with Cladosporium spp. Sequencing of the internal transcribed spacer region identified the fungus as a species of the Cladosporium cladosporioides-complex.

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Section: Discussionmentioning

confidence: 99%

Cladosporium cladosporioides‐complex infection in a mixed‐breed dog

Spano

Zuliani

Peano

et al. 2018

Veterinary Clinical Pathol

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“…In addition to these cases, there are some reports of animal infections where species-level confirmation had not been performed but which were probably due to C. bantiana (25)(26)(27)(28). In addition to the equine case of this report, animal species affected by this fungus include cats (20,23,(29)(30)(31)(32)(33), dogs (21, 27, 34-36), a snow leopard (24), and an alpaca (37). The predilection of this fungus for the central nervous system (CNS) is also apparent in animals: 58% of previously reported cases had lesions in the brain, and the clinical signs in these were similar to those of humans.…”

mentioning

confidence: 83%

“…Dissemination of the disease in animals is common, since in 50% (12/24) of cases, lesions in various internal organs were observed with (n ϭ 5) or without (n ϭ 7) CNS in- Case Report volvement. Dark or black lesions in internal organs and the CNS are a characteristic feature of systemic C. bantiana infections (8,20,24,36,38). As in humans, the outcome of cerebral or systemic phaeohyphomycosis is often fatal, but local infections may have a better prognosis, provided that surgery and long-term medical treatment are combined.…”

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confidence: 99%

Cladophialophora bantiana as an Emerging Pathogen in Animals: Case Report of Equine Endometritis and Review of the Literature

et al. 2015

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We present an unusual equine endometritis case associated with Cladophialophora bantiana in a 15-year-old mare. The mare displayed infertility and uterine fluid accumulation with numerous black, hairy granules. Microscopically, the fluid revealed numerous septate, dark fungal hyphae and conidia in chains. Culture yielded C. bantiana (CBS 138271); the species was confirmed by internal transcribed spacer (ITS) sequencing. Treatment was unsuccessful. C. bantiana causes cerebral phaeohyphomycosis in humans, while animal cases are rare. Animal cases are reviewed. CASE REPORT

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“…Pigmented hyphae were numerous throughout the lesions and occasionally within lateral ventricles of brain (97,98).…”

Section: Cats and Dogsmentioning

confidence: 98%

Phaeohyphomycoses, Emerging Opportunistic Diseases in Animals

2013

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SUMMARYEmerging fungal diseases due to black yeasts and relatives in domestic or wild animals and in invertebrates or cold- and warm-blooded vertebrates are continually being reported, either as novel pathogens or as familiar pathogens affecting new species of hosts. Different epidemiological situations can be distinguished, i.e., occurrence as single infections or as zoonoses, and infection may occur sporadically in otherwise healthy hosts. Such infections are found mostly in mammals but also in cold-blooded animals, are frequently subcutaneous or cerebral, and bear much similarity to human primary disorders. Infections of the nervous system are mostly fatal, and the source and route of infection are currently unknown. A third epidemiological situation corresponds to pseudoepidemics, i.e., infection of a large host population due to a common source. It is often observed and generally hypothesized that the susceptible animals are under stress, e.g., due to poor housing conditions of mammals or to a change of basins in the case of fishes. The descriptions in this article represent an overview of the more commonly reported and recurring black fungi and the corresponding diseases in different types of animals.

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Phaeohyphomycosis in a Snow Leopard (Uncia uncia) due to Cladophialophora bantiana

Cited by 10 publications

References 11 publications

Cladosporium cladosporioides‐complex infection in a mixed‐breed dog

Cladosporium cladosporioides‐complex infection in a mixed‐breed dog

Cladophialophora bantiana as an Emerging Pathogen in Animals: Case Report of Equine Endometritis and Review of the Literature

Phaeohyphomycoses, Emerging Opportunistic Diseases in Animals

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