Phaeochromocytoma presenting acutely as severe cardiac failure.

Connolly, D L; Mariathas, D A

doi:10.1136/emj.11.2.125

Cited by 4 publications

(4 citation statements)

References 5 publications

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“…In these patients, despite coronary–artery normality, acute heart failure with pulmonary oedema is possible [ 32 ]. The presence of pheochromocytomas may cause the same electrocardiographic changes as acute myocardial infarction [ 33 , 34 ], malignant cardiac arrhythmia, and even dissecting aortic aneurysm. Sudden death, heart failure (due to toxic cardiomyopathy), hypertensive encephalopathy, acute cerebrovascular event, or neurogenic pulmonary oedema are other possible cardiovascular complications in patients with pheochromocytoma [ 35 , 36 , 37 ].…”

Section: Discussionmentioning

confidence: 99%

When a Multidisciplinary Approach Is Life-Saving: A Case Report of Cardiogenic Shock Induced by a Large Pheochromocytoma

et al. 2022

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Background: Pheochromocytoma is known for its instantaneous presentation, especially in the younger population. Hemodynamic instability may be the cause of severe complications and impede patients’ ability to undergo surgical treatment. These tumours are surgically difficult to treat due to the risk of catecholamine release during their manipulations, and when they are large, the tumour size represents an additional challenge. In our report, cardiogenic shock developed due to increases in systemic vascular resistance, and the lesion’s size induced surgeons to perform open surgery. Case presentation: A 46-year-old female patient was admitted to our intensive care unit with hypertension and later cardiogenic shock. Systolic dysfunction was noted, along with severely increased systemic vascular resistance. A CT scan showed a left-sided 8.5 cm adrenal mass, which was confirmed as pheochromocytoma using meta-iodobenzylguanidine scintigraphy. Anaesthesiologists and the surgical team planned an effective strategy of treatment. Given the lesion’s size and its apparent invasion of the neighbouring organs, open adrenalectomy (after prolonged hemodynamic stabilisation) was considered safer. The surgery was successful, and the patient remains free from disease two years after the initial event. Conclusions: Large pheochromocytoma can be safely and effectively treated with open surgery by experienced hands but only by seeking to reach hemodynamic stabilisation and minimising the release of catecholamine before and during surgery.

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Section: Discussionmentioning

confidence: 99%

When a Multidisciplinary Approach Is Life-Saving: A Case Report of Cardiogenic Shock Induced by a Large Pheochromocytoma

et al. 2022

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“…20,21 Although it is rare, myocardial involvement other than sustained or paroxysmal hypertension, from a pheochromocytoma can include angina pectoris, acute heart failure, dilated cardiomyopathy, myocardial infarction, and arrhythmias. [22][23][24][25][26] The acute onset of severe congestive heart failure secondary to catecholamine overproduction from a pheochromocytoma is a rare entity, especially when few or none of the other classic signs or symptoms are present. Our patient presented in such a manner, and if not for abdominal distention prompting evaluation with helical CT and subsequent finding of a right adrenal mass, the differential diagnosis of a pheochromocytoma may not have been entertained as quickly.…”

Section: Discussionmentioning

confidence: 99%

Pheochromocytoma Presenting as Acute Severe Congestive Heart Failure, Dilated Cardiomyopathy, and Severe Mitral Valvular Regurgitation: A Case Report and Review of the Literature

Kelley

Goel

Smith

2009

Journal of Surgical Education

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“…Pheochromocytoma may present as acute heart failure and pulmonary edema, despite coronary-artery normality [5], and may mediate acute electrocardiographic changes mimicking acute myocardial infarction (AMI) [6,7], malignant cardiac arrhythmia and even dissecting aortic aneurysm.…”

Section: Disscusionmentioning

confidence: 99%

“…The serious and potentially lethal cardiovascular complications of these tumors are due to the potent effects of secreted catecholamines [ 4 ]. Pheochromocytoma may present as acute heart failure and pulmonary edema, despite coronary-artery normality [ 5 ], and may mediate acute electrocardiographic changes mimicking acute myocardial infarction (AMI) [ 6 , 7 ], malignant cardiac arrhythmia and even dissecting aortic aneurysm.…”

Section: Disscusionmentioning

confidence: 99%

Emergency adrenalectomy due to acute heart failure secondary to complicated pheochromocytoma: a case report

et al. 2011

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Pheochromocytomas are catecholamine producing tumors arising mostly from chromaffin cells of the adrenal medulla. The most common clinical presentation is hypertension, mainly in the form of paroxymal episodes. Cardiovascular manifestations include malignant arrhythmia and catecholamine cardiomyopathy, mimicking acute coronary syndromes and acute heart failure.There are reports of pheochromocytomas presenting as acute coronary syndrome and rapidly leading to cardiogenic shock; the failure of intensive medical treatment in these cases has prompted the need for emergency adrenalectomy as the only remaining option. We report on a case of complicated pheochromocytoma presenting as cardiogenic shock, in which emergency adrenalectomy was performed following a total lack of response to intensive medical treatment.

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Phaeochromocytoma presenting acutely as severe cardiac failure.

Cited by 4 publications

References 5 publications

When a Multidisciplinary Approach Is Life-Saving: A Case Report of Cardiogenic Shock Induced by a Large Pheochromocytoma

When a Multidisciplinary Approach Is Life-Saving: A Case Report of Cardiogenic Shock Induced by a Large Pheochromocytoma

Pheochromocytoma Presenting as Acute Severe Congestive Heart Failure, Dilated Cardiomyopathy, and Severe Mitral Valvular Regurgitation: A Case Report and Review of the Literature

Emergency adrenalectomy due to acute heart failure secondary to complicated pheochromocytoma: a case report

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