pH-Sensitive Nanocapsules with Barrier Properties: Fragrance Encapsulation and Controlled Release

Hofmeister, Ines; Landfester, Katharina; Taden, Andreas

doi:10.1021/ma501388w

Cited by 81 publications

(73 citation statements)

References 30 publications

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“…Changes in temperature can promote core release, either by temperature-sensitive release, where materials expand or collapse when a critical temperature is reached, or by fusion-activated release, which involves melting of the shell material due to temperature increase. Hofmeister et al, (2014) presented a facile synthesis method for polymer nanocapsules with high diffusion barrier and stimuli-responsive release properties: temperature and pH change can be used as trigger to open the capsules, and the release kinetics can be tailored depending on the polymer shell composition. Pressure release occurs when pressure is applied to the capsule wall, e.g.…”

Section: Controlled Releasementioning

confidence: 99%

Encapsulation of cosmetic active ingredients for topical application – a review

Casanova

Santos

2015

Journal of Microencapsulation

191

115

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Abstract:Microencapsulation is finding increasing applications in cosmetics and personal care markets. This paper provides an overall discussion on encapsulation of cosmetically active ingredients and encapsulation techniques for cosmetic and personal care products for topical applications. Some of the challenges are identified and critical aspects and future perspectives are addressed. Many cosmetics and personal care products contain biologically active substances that require encapsulation for increased stability of the active materials. The topical and transdermal delivery of active cosmetic ingredients requires effective, controlled and safe means of reaching the target site within the skin. Preservation of the active ingredients is also essential during formulation, storage and application of the final cosmetic product.Microencapsulation offers an ideal and unique carrier system for cosmetic active ingredients, as it has the potential to respond to all these requirements. The encapsulated agent can be released by several mechanisms, such as mechanical action, heat, diffusion, pH, biodegradation and dissolution. The selection of the encapsulation technique and shell material depends on the final application of the product, considering physical and chemical stability, concentration, required particle size, release mechanism and manufacturing costs.

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Section: Controlled Releasementioning

confidence: 99%

Encapsulation of cosmetic active ingredients for topical application – a review

Casanova

Santos

2015

Journal of Microencapsulation

191

115

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“…In the last decade, Landfester, Crespy and co-workers carried out several comprehensive studies [27][28][29][30][31][32]35] where various aspects related to the preparation of nanoand microcapsules on the emulsion basis and to their final morphology (core-shell, compact etc.) were investigated.…”

Section: · Author Manuscriptmentioning

confidence: 99%

“…were investigated. Influence of numerous physicochemical parameters such as concentrations and hydrophobicity of solvent and polymer components in the dispersed "oil" phase [27,28,30,32]; rate of the reactants addition during interfacial polycondensation reaction [27]; nature of copolymers [28] and surfactants (interfacial tension) used for the emulsification [28,29]; inversion of polar/apolar continuous vs. dispersed phases [30]; temperature [28][29][30] on the formation, properties and morphology of capsules were analyzed.…”

Section: · Author Manuscriptmentioning

confidence: 99%

Microgel containers for self-healing polymeric materials: Morphology prediction and mechanism of formation

Latnikova

Grigoriev

Möhwald

et al. 2015

Polymer

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Abstract18 types of gel microparticles, composed of 3 polymer types and 6 different solvents, were prepared by interfacial polymerization and compared in a systematic way with respect to their structure and function. Three types of morphologies, specific for each polymer-solvent pair, were observed: core-shell, multicompartment and compact. The morphology was found to be a direct consequence of the specific polymer-solvent interactions and can be, in most cases, predicted on the basis of simple swelling experiments with a chosen polymer in the solvent. Further, the Hansen Solubility Parameters approach was applied to the investigated systems enabling a reliable morphology prediction of microgel particles made of any polymer/solvent combination with known solubility parameters (spheres). The mechanisms responsible for the formation of particles with different morphologies are also discussed. were prepared by interfacial polymerization and compared in a systematic way with respect to their structure and function. Three types of morphologies, specific for each polymer-solvent pair, were observed: core-shell, multicompartment and compact. The morphology was found to be a direct consequence of the specific polymer-solvent interactions and can be, in most cases, predicted on the basis of simple swelling experiments with a chosen polymer in the solvent. Further, the Hansen Solubility Parameters approach was applied to the investigated systems enabling a reliable morphology prediction of microgel particles made of any polymer/solvent combination with known solubility parameters (spheres). The mechanisms responsible for the formation of particles with different morphologies are also discussed. Max Planck Institute of Colloids and Interfaces · Author Manuscript MPIKG Public Access

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“…The intelligent microcapsule can respond to external stimuli changes such as temperature 5 , pH value 6 , ionic strength 7 , light 8 and electric fields 9 , etc. Among the intelligent microcapsules, pH/ temperature sensitive microcapsules have been widely investigated in the biomedical fields due to the easy controlling and applications both in vitro and in vivo conditions 10,11 .…”

Section: Introductionmentioning

confidence: 99%

Untitled

2017

IJPSR

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ABSTRACT:The pH/temperature sensitive microcapsules were prepared by inverse emulsion polymerization, in which sodium alginate (SA) and N-isopropyl acrylamide (NIPAm) were used as the wall material and pentoxifylline as a model drug. The effects of the emulsifier content on the particle size distribution and drug release property of microcapsules were discussed in detail. The structure, morphology, particle size and its distribution of microcapsules were characterized by Fourier transform infrared spectrophotometry (FTIR), scanning electron microscopy (SEM), transmission electron microscope (TEM), Malvern particle size analysis and UV-vis spectrophotometer. The release behavious of pentoxifylline in different phosphate buffered saline (PBS) pH were investigated systematically. The results showed that the resultant microcapsules had narrower particle size distribution, smoother surface and higher drug release amount with the percentage weight of emulsifier being 2.0%. The TEM photograph exhibited that the microcapsules had core and shell structures. The drug-release behavior of pentoxifylline from microcapsules was evaluated as a function of pH/temperature. The results indicated that these drug-loaded microcapsules have shown sensitivity to pH value and temperature.

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pH-Sensitive Nanocapsules with Barrier Properties: Fragrance Encapsulation and Controlled Release

Cited by 81 publications

References 30 publications

Encapsulation of cosmetic active ingredients for topical application – a review

Encapsulation of cosmetic active ingredients for topical application – a review

Microgel containers for self-healing polymeric materials: Morphology prediction and mechanism of formation

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