2023
DOI: 10.1016/j.jddst.2023.104960
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pH-responsive MTX-BSA@MnO2-Cy5.5 for NIRF/MR imaging guided chemotherapy of anaplastic thyroid carcinoma

Zhengrong Xie,
Qiushi Jia,
Shuang Wu
et al.
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“…For instance, Xie et al used BSA-biomineralized MnO 2 as a carrier for loading the anti-tumor drug methotrexate (MTX) and fluorescent dye Cy5.5 through amide condensation, to prepare the nanodrug MTX-BSA@MnO 2 -Cy5.5 (MBMC NPs). 99 The designed MBMC NPs are for the diagnosis and treatment of anaplastic thyroid carcinoma. MBMC NPs showed good pH-responsive drug release and imaging performance.…”
Section: Biomedical Applicationsmentioning
confidence: 99%
“…For instance, Xie et al used BSA-biomineralized MnO 2 as a carrier for loading the anti-tumor drug methotrexate (MTX) and fluorescent dye Cy5.5 through amide condensation, to prepare the nanodrug MTX-BSA@MnO 2 -Cy5.5 (MBMC NPs). 99 The designed MBMC NPs are for the diagnosis and treatment of anaplastic thyroid carcinoma. MBMC NPs showed good pH-responsive drug release and imaging performance.…”
Section: Biomedical Applicationsmentioning
confidence: 99%