pH-Regulated Terbium(III) Infinite Coordination Polymer Sensor Array for Pattern Discrimination of Quinolone Antibiotics

Abstract

In this study, dual-ligand lanthanide metal−organic infinite coordination polymer (BDC-NH 2 -Tb-AMP ICPs) with dual fluorescence emission was constructed. Considering that quinolone antibiotics can sensitize Tb 3+ luminescence, the diverse fluorescence responses for different antibiotics on Tb 3+ at various pH's are distinct due to their structures. Inspired by these facts, a fluorescent sensor array, in which the pH-regulated BDC-NH 2 -Tb-AMP ICPs acted as the sensing element, was proposed for the pattern recognition of five representative quinolone antibiotics using principal component analysis. Furthermore, the sensor array can realize the detection of environmental quinolone antibiotics in real samples, confirming its reliability and practicality in complex conditions. More broadly, by using the simple yet powerful strategy of pH regulation, the presented sensor array holds a great ability for efficiently distinguishing quinolone antibiotics, which provides an approach for point-ofcare monitoring of residual antibiotics in the environmental field.