pH-Metric Studies of Mixed Ligand Complexes of Zn(II) with Famotidine and peptides

Abstract

Solution equilibria of the ternary complexes of Zn(II) with famotidine (FAM) as primary ligand and peptides (L) as secondary ligands have been studied pH-metrically under the experimental conditions (25°C and ionic strength I = 0.10 mol/L NaNO 3 ). Ternary complexes are formed by a simultaneous mechanism. The concentration distribution of the complexes in solution was evaluated as a function of pH. The values of Δ log K values for the ternary complexes have been evaluated and discussed.