With the development of society, e-commerce competition has become increasingly intense and has ascended to the level of the ecosystem. Therefore, it is extremely significant to study the mechanism of evolution and balance for the e-commerce ecosystem. Simultaneously, blockchain technology is essentially a consensus mechanism, the core idea of which is decentralization, but it is actually the deconstruction of privileges and authority. Especially, the influence on the e-commerce ecosystem cannot be underestimated. Blockchain technology ultimately changes not only technology, but a comprehensive reconstruction of various industries. Building an e-commerce information ecosystem based on blockchain can promote the healthy and sustainable development of e-commerce information ecology. This work combines the definition and technical characteristics of blockchain, discusses the blockchain-based e-commerce information ecosystem model, and discusses how to achieve the ecological balance and system evolution of e-commerce under the background of blockchain. According to the internal problems of the e-commerce ecosystem, three evolutionary paths are proposed in this work. First, consider the timeliness of the information and construct a full-process information channel. Second, remove central nodes and build a safe and efficient block payment. Third, solve the blind zone in the field of logistics and create efficient and transparent intelligent logistics. This work can provide an effective reference for the development of e-commerce.