Pesticidal activities of some 3-aryl-4-methylpyrazolo[3,4-b][1,5]benzodiazepines and 4-aryl-2-imino-5-methyl-1,3-thiazino[4,5-b][1,5]benzodiazepines

Abstract

A number of 3-aryl-4-methylpyrazolo[3,4-b1~1,5lbenzodiazepines and 4-aryl-2-imino-5-methyl-1,3-thiazino[4,5-b1[1,5lbenzodiazepines have been synthesized from 3-(arylmethylene)-4-methyl-1,5-benzodiazepin-2-one by cyclocondensation with hydrazine hydrate and thiourea in basic medium, respectively. All of the compounds were evaluated for their insecticidal and fungistatic activities, and the results are compared with the standard insecticide Propoxure and the standard fungicide Maneb. Some structure-activity relationships are discussed on the basis of screening data.

Synthesis and Biological Evaluation of Triazole linked Thiazolidenone Glycosides

“…Thiazolidenone and its derivatives are known to possess significant pharmacological 6 and biological activities, 7 like sedative, 8 anti inflammatory, 9 anti tubercular, 10 anticancer, 11 antitumor, 12 anti-HIV, 13 antibacterial, 14 antifungal, 15 analgesic, hypothermic, 16 anesthetic, 17 nematicidal 18 and CNS stimulant. 19 Furthermore, thiazolidenones have been used for the treatment of cardiac diseases, 20 diabetic complications, like cataract nephropathy, neuropathy, 21 and as selective anti platelet activating factor.…”

Synthesis, Characterization and Antimicrobial Activity of Some Novel 1,3,4-Oxadiazole Based Dithiaza-Spirones

“…Different classes of oxadiazole compounds possess an extensive spectrum of pharmacological activities such as antibacterial 1 , antimalarial 2 , anti-inflammatory 3 , antifungal 4 , anticonvulsant 5 , analgesic 6 antimycobacterial 7 , antitumor 8 , herbicidal 9 , vasodialatory 10 , cytotoxic 11 , hypolipidemic 12 , ulcerogenic 13 and antiedema 14 . Numerous thiazolidinone derivatives have shown significant pharmacological and biological activities 15 like sedative 16 , antiinflammatory 17 , antibacterial 18 , antifungal 19 , antitubercular 20 , anticancer 21 , hypnotic 22 , anti-HIV 23 and nematicidal 24 .…”

Crystal and molecular structure of bis(4-bromo-N-(di-n-butylcarbamothioyl)benzamido) copper(II) complex

“…Substituted N,N-dialkyl-N'-benzoylthioureas are interesting compounds that are utilized in medicinal as antibacterial [6][7][8], antifungal [9,10], antiviral [11], pesticidal [12], cancerostatic [13] and cytotoxic [14] agents. In analytical chemistry, thioureas have been used as extraction agents for transition group metal ions [15].…”