Pertussis in adults

Mannerstedt, Gordon

doi:10.1016/s0022-3476(34)80039-x

Cited by 33 publications

(5 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…An analysis of surveillance data from the prevaccine era of reported pertussis would suggest that pertussis was a rarity in adults (141). However, the experts at the time clearly recognized that atypical pertussis was not uncommon in adults and that these illnesses were reinfections (141,442,478,492).…”

Section: Pathogenesis and Immunitymentioning

confidence: 99%

Molecular Pathogenesis, Epidemiology, and Clinical Manifestations of Respiratory Infections Due toBordetella pertussisand OtherBordetellaSubspecies

2005

View full text Add to dashboard Cite

Bordetella respiratory infections are common in people (B. pertussis) and in animals (B. bronchiseptica). During the last two decades, much has been learned about the virulence determinants, pathogenesis, and immunity of Bordetella. Clinically, the full spectrum of disease due to B. pertussis infection is now understood, and infections in adolescents and adults are recognized as the reservoir for cyclic outbreaks of disease. DTaP vaccines, which are less reactogenic than DTP vaccines, are now in general use in many developed countries, and it is expected that the expansion of their use to adolescents and adults will have a significant impact on reducing pertussis and perhaps decrease the circulation of B. pertussis. Future studies should seek to determine the cause of the unique cough which is associated with Bordetella respiratory infections. It is also hoped that data gathered from molecular Bordetella research will lead to a new generation of DTaP vaccines which provide greater efficacy than is provided by today's vaccines

show abstract

Section: Pathogenesis and Immunitymentioning

confidence: 99%

Molecular Pathogenesis, Epidemiology, and Clinical Manifestations of Respiratory Infections Due toBordetella pertussisand OtherBordetellaSubspecies

2005

View full text Add to dashboard Cite

show abstract

“…And even today, most adult cases are initially misdiagnosed. In the 1930s, many physicians with an interest in pertussis recognized adult pertussis but underestimated its prevalence [58,62].…”

Section: Epidemiologymentioning

confidence: 99%

The History of Pertussis (Whooping Cough); 1906–2015: Facts, Myths, and Misconceptions

Cherry

2015

Curr Epidemiol Rep

View full text Add to dashboard Cite

Pertussis and Bordetella pertussis infections since 1906 are reviewed with an attempt to address facts, myths, and misconceptions. Clinical pertussis is a noninflammatory illness which occurs without fever or productive cough, and its hallmark is the distinctive paroxysmal cough. Because of its significant mortality and morbidity, whole-cell vaccines were developed in the 1930s, and the universal use of these vaccines decreased the incidence of reported pertussis 157-fold by 1970. Because of real and perceived reactions to diphtheria and tetanus toxoids and whole cell pertussis vaccine (DTwP) vaccines, diphtheria and tetanus toxoids and acellular pertussis vaccine (DTaP) vaccines were developed and put into universal use in the USA in 1997. Pertussis has two epidemiologies; one is reported pertussis and the other is B. pertussis illness. The study of these two epidemiologies indicate that reported pertussis is just the tip of the iceberg and B. pertussis cough illnesses occur in all age groups and they are very common; also, asymptomatic infection is more common than symptomatic infection. DTaP vaccines are less reactogenic than DTwP vaccines, but their effectiveness is less. B. pertussis infection is caused by many protein antigens, but illness due to this organism is caused by just two factors, pertussis toxin (PT) and a Bcough toxinŵ hich, as yet, has not been discovered. The present Bresurgence of pertussis^is mainly due to greater awareness and the use of PCR for diagnosis. There are also many other factors which have contributed to the Bresurgence.^New vaccines are clearly needed; with our present vaccines (DTaP and adolescent and adult formulated tetanus and diphtheria toxoids and acellular pertussis vaccine (Tdap)), if used correctly, severe pertussis and deaths in infants can be prevented.

show abstract

“…Pertussis can present atypically in adults, and asymptomatic cases of pertussis in adults are common [ 5 , 6 ]. However, pertussis can also be debilitating in this population with complications, including pneumonia, fainting, urinary incontinence, rib fracture, encephalopathy, and worsening of underlying respiratory conditions [ 7 , 8 ].…”

Section: Introductionmentioning

confidence: 99%

Risk Factors of Pertussis Among Older Adults in South Korea: A Nationwide Health Data-Based Case–Control Study

Kim

Shin

Chen³

et al. 2023

Infect Dis Ther

View full text Add to dashboard Cite

Introduction: To better understand the conditions associated with pertussis diagnosis among older adults in South Korea, a matched case-control study was conducted of individuals C 50 years diagnosed with pertussis between 2009 and 2018. Methods: Pertussis cases were identified using the nationwide Health Insurance Review and Assessment service (HIRA) database. Each case was then matched to up to 10 controls identified using the National Health Insurance Service-National Sample Cohort (NHIS-NSC) by age, sex, and geographic region at index date. In the 12 months and 30 days prior to index date,

show abstract

Pertussis in adults

Cited by 33 publications

References 2 publications

Molecular Pathogenesis, Epidemiology, and Clinical Manifestations of Respiratory Infections Due toBordetella pertussisand OtherBordetellaSubspecies

Molecular Pathogenesis, Epidemiology, and Clinical Manifestations of Respiratory Infections Due toBordetella pertussisand OtherBordetellaSubspecies

The History of Pertussis (Whooping Cough); 1906–2015: Facts, Myths, and Misconceptions

Risk Factors of Pertussis Among Older Adults in South Korea: A Nationwide Health Data-Based Case–Control Study

Contact Info

Product

Resources

About