Risk Factors of Pertussis Among Older Adults in South Korea: A Nationwide Health Data-Based Case–Control Study

Kim, Hyungwoo; Shin, Ju Young; Chen, Jing; Kim, Juhwan; Noh, Yunha; Cheong, Hee Jin; Oh, Yeon Mok; Guignard, Adrienne; Shantakumar, Sumitra

doi:10.1007/s40121-022-00747-0

Cited by 4 publications

(2 citation statements)

References 27 publications

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“…However, since PFT may not be readily available in local hospitals, it leads to an excessive diagnosis of asthma even in adult patients because diagnosing asthma does not require PFT according to the policy. Therefore, in a study conducted with the national healthcare database of South Korea, asthma and COPD are often reported as a composite termasthma/COPD (40)(41)(42) because they are hard to distinguish from each other in this unique setting of clinical practice. As the diagnosis of the diseases was operationally defined using diagnostic codes, it could be inaccurate and possibly overestimated.…”

Section: Discussionmentioning

confidence: 99%

Chronic airway disease as a major risk factor for fractures in osteopenic women: Nationwide cohort study

Kong

Jo²,

Park³

et al. 2023

Front. Endocrinol.

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IntroductionThe study aimed to demonstrate the risk factors for fractures and to develop prediction models for major osteoporotic and hip fractures in osteopenic patients using the nationwide cohort study in South Korea.MethodsThe study was a retrospective nationwide study using the national screening program for transitional ages from the National Health Insurance Services database in Korea from 2008 to 2019. Primary outcomes were incident fracture events of major osteoporotic and hip fractures. Major osteoporotic and hip fracture events were defined as diagnostic and procedural codes. Patients were followed until the fragility fractures, death, or 2019, whichever came first.ResultsAll participants were 66-year-old females, with a mean body mass index was 25.0 ± 3.1 kg/m2. During a median follow-up of 10.5 years, 26.9% and 6.7% of participants experienced major osteoporotic and hip fractures. In multivariate analysis, a history of fracture, chronic airway disease, falls, diabetes mellitus and cerebrovascular diseases were significant risk factors for major osteoporotic (hazard ratio [HR] 2.35 for a history of fracture; 1.17 for chronic airway disease; 1.10 for falls; 1.12 for diabetes mellitus; 1.11 for cerebrovascular disease) and hip fractures (HR 1.75 for a history of fracture; 1.54 for diabetes mellitus; 1.27 for cerebrovascular disease; 1.17 for fall; 1.15 for chronic airway disease). The performances of the prediction models were area under the receiver operating curve of 0.73 and 0.75 for major osteoporotic and hip fractures.ConclusionThe study presented prediction models of major osteoporotic and hip fractures for osteopenia patients using simple clinical features.

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Section: Discussionmentioning

confidence: 99%

Chronic airway disease as a major risk factor for fractures in osteopenic women: Nationwide cohort study

Kong

Jo²,

Park³

et al. 2023

Front. Endocrinol.

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“…In a retrospective cohort study from the UK, the incidence of pertussis among individuals aged ≥50 years with COPD was assessed from Clinical Practice Research Datalink and Hospital Episode Statistics databases during 2009–2018 [ 134 ]. COPD patients had a 2.32-fold higher risk of contracting pertussis resulted in significant increases in healthcare resource utilisation and direct medical costs around the pertussis event [ 134 , 135 ]. New and immunologically improved vaccines will be expected in the next few years.…”

Section: Pertussis Vaccinementioning

confidence: 99%

The role of vaccination in COPD: influenza, SARS-CoV-2, pneumococcus, pertussis, RSV and varicella zoster virus

Simon,

Joean,

Welte

et al. 2023

Eur Respir Rev

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Exacerbations of COPD are associated with worsening of the airflow obstruction, hospitalisation, reduced quality of life, disease progression and death. At least 70% of COPD exacerbations are infectious in origin, with respiratory viruses identified in approximately 30% of cases. Despite long-standing recommendations to vaccinate patients with COPD, vaccination rates remain suboptimal in this population.Streptococcus pneumoniaeis one of the leading morbidity and mortality causes of lower respiratory tract infections. The Food and Drug Administration recently approved pneumococcal conjugate vaccines that showed strong immunogenicity against all 20 included serotypes. Influenza is the second most common virus linked to severe acute exacerbations of COPD. The variable vaccine efficacy across virus subtypes and the impaired immune response are significant drawbacks in the influenza vaccination strategy. High-dose and adjuvant vaccines are new approaches to tackle these problems. Respiratory syncytial virus is another virus known to cause acute exacerbations of COPD. The vaccine candidate RSVPreF3 is the first authorised for the prevention of RSV in adults ≥60 years and might help to reduce acute exacerbations of COPD. The 2023 Global Initiative for Chronic Lung Disease report recommends zoster vaccination to protect against shingles for people with COPD over 50 years.

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Epidemiology of Pertussis and Pertussis-Related Complications in Adults: A German Claims Data Analysis

Surmann,

Witte,

Batram

et al. 2024

Infect Dis Ther

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Risk Factors of Pertussis Among Older Adults in South Korea: A Nationwide Health Data-Based Case–Control Study

Cited by 4 publications

References 27 publications

Chronic airway disease as a major risk factor for fractures in osteopenic women: Nationwide cohort study

Chronic airway disease as a major risk factor for fractures in osteopenic women: Nationwide cohort study

The role of vaccination in COPD: influenza, SARS-CoV-2, pneumococcus, pertussis, RSV and varicella zoster virus

Epidemiology of Pertussis and Pertussis-Related Complications in Adults: A German Claims Data Analysis

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