Perspectives of Genetic Damage and Epigenetic Alterations by Hexavalent Chromium: Time Evolution Based on a Bibliometric Analysis

Abstract

Compounds containing hexavalent chromium [Cr-(VI)] have been classified as Group I human carcinogens in 1990 by the International Agency for Research on Cancer, known to induce human lung cancers. To determine the nature of Cr(VI) carcinogenesis, much has been learned about genetic damage and epigenetic alterations. On the basis of bibliometric analysis of the available literature found between 1966 and 2020, the present study investigated the evolution of author keywords; provided a summary of relevant studies focused on populations, animals/ plants, or cells; and depicted the co-operation among countries or institutions and research group development. Additionally, multiomics technology and bioinformatics analysis can be a valuable tool for figuring out new biomarkers from different molecular levels like gene, RNA, protein, and metabolite and ascertaining the mechanism pathways of Cr(VI) genotoxicity and carcinogenesis.

Hexavalent Chromium Removal from Industrial Wastewater by Adsorption and Reduction onto Cationic Cellulose Nanocrystals

“…The presence of chromium in water effluents is related to several environmental concerns since it is cytotoxic and carcinogen to a wide range of species, along with other acute affections [ 1 , 2 , 3 ]. Chromium is typically present as hexavalent and trivalent species, although the environmental impact associated with chromium presence would vary depending on the species: while hexavalent is highly toxic, bioaccumulable and persistent in nature, even at low concentrations, the trivalent one shows less cytotoxicity [ 4 ].…”

Selective removal of Cr2O72− in aqueous solution by nonporous pure crystals of cucurbit[6]uril

“…3 Due to its ultrahigh toxicity, chromate has been classified as a group-I carcinogen by the International Agency for Research on Cancer (IARC) and listed as a priority pollutant by many countries. 4 Therefore, it is of great importance to remove chromate from water and various strategies have been established in the past several decades for the treatment of chromate anions, including ion exchange, absorption, photocatalytic reduction/degradation, biological treatment and so on. 5 Compared to other technologies, adsorption has been recognized as one of the most promising approaches for the removal of chromate due to its simplicity, low cost and high efficiency, and the exploitation of superior adsorbents for chromate removal has become a subject of intensive research in recent years.…”