Personality disorders in bipolar and depressive disorders

Rossi, Alessandro; Marinangeli, Maria Grazia; Butti, Giancarlo; Scinto, Antonella; Cicco, Loredana Di; Kalyvoka, Artemis; Petruzzi, Concetta

doi:10.1016/s0165-0327(00)00230-5

Cited by 74 publications

(37 citation statements)

References 22 publications

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“…11,38 In our review, borderline PD was the most frequent comorbid PD in bipolar patients, with a rate of 10%, tenfold that observed in the general population. 39 However, reported rates varied broadly, ranging from 6.2 to 30% in BD type I 7,[19][20][21]40 and 12 to 23% in BD type II. 16,41,42 On the other hand, comorbid antisocial PD was very infrequent in the studies included in our review (0.79%), and seems to be more common in BD type I than in type II.…”

Section: Discussionmentioning

confidence: 99%

“…5 Part of these losses are also due to high rates of comorbidity with psychiatric axis I and II disorders, with therapeutic and prognostic implications. 6,7 Among the comorbidities of greater impact in patients with BD are personality disorders (PDs). Several studies have shown that the co-occurrence of BD and PD generates a negative impact on response to treatment, increased suicidal behavior, and reduced global functioning in bipolar patients.…”

Section: Introductionmentioning

confidence: 99%

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Personality disorders in euthymic bipolar patients: a systematic review

Bezerra-Filho

Almeida

Studart

et al. 2015

Rev. Bras. Psiquiatr.

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Objective: To identify, by means of a systematic review, the frequency with which comorbid personality disorders (PDs) have been assessed in studies of euthymic bipolar patients. Methods: PubMed, SciELO and PsychINFO databases were searched for eligible articles published between 1997 and 2013. After screening 1,249 empirical papers, two independent reviewers identified three articles evaluating the frequency of PDs in patients with bipolar disorders assessed in a state of euthymia.Results: The total sample comprised 376 euthymic bipolar patients, of whom 155 (41.2%) had at least one comorbid PD. Among them, we found 87 (23.1%) in cluster B, 55 (14.6%) in cluster C, and 25 (6.6%) in cluster A. The frequencies of PD subtypes were: borderline, 38 (10.1%); histrionic, 29 (7.7%); obsessive-compulsive, 28 (7.4%); dependent, 19 (5%); narcissistic, 17 (4.5%); schizoid, schizotypal, and avoidant, 11 patients each (2.95%); paranoid, five (1.3%); and antisocial, three (0.79%). Conclusion: The frequency of comorbid PD was high across the spectrum of euthymic bipolar patients. In this population, the most common PDs were those in cluster B, and the most frequent PD subtype was borderline, followed by histrionic and obsessive-compulsive.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Personality disorders in euthymic bipolar patients: a systematic review

Bezerra-Filho

Almeida

Studart

et al. 2015

Rev. Bras. Psiquiatr.

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“…OCPD has also been found to be the most frequent personality disorder co-occurring with anorexia nervosa-restricting type, binge eating disorder, 100 and bipolar disorder. 101,102 OCPD also co-occurs in 31% of cases of major depressive disorder 101,103 and17% of cases of panic disorder. 18 All these disorders also show high levels of comorbidity with OCD.…”

Section: Comorbiditymentioning

confidence: 99%

Obsessive-compulsive (anankastic) personality disorder: toward the ICD-11 classification

Fineberg

Reghunandanan

Kolli

et al. 2014

Rev. Bras. Psiquiatr.

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Obsessive-compulsive personality disorder (OCPD) is an early-onset disorder characterized by perfectionism, need for control, and cognitive rigidity. Its nosological status is currently under review. Historically, OCPD has been conceptualized as bearing a close relationship with obsessivecompulsive disorder (OCD). In this article, we discuss the diagnosis of OCPD in anticipation of its review for the ICD-11, from the perspective of clinical utility, global applicability, and research planning. Considering the recent establishment of an obsessive-compulsive and related disorders (OCRD) category in DSM-5, we focus on the relationship between OCPD and the disorders that are currently thought to bear a close relationship with OCD, including DSM-5 OCRD, and other compulsive disorders such as eating disorder and autistic spectrum disorder (that were not included in the DSM-5 OCRD category), as well as with the personality disorders, focusing on nosological determinants such as phenomenology, course of illness, heritability, environmental risk factors, comorbidity, neurocognitive endophenotypes, and treatment response. Based on this analysis, we attempt to draw conclusions as to its optimal placement in diagnostic systems and draw attention to key research questions that could be explored in field trials.

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“…Lifetime prevalence rates of personality disorders in patients with bipolar disorders, range from 29% to 48% (Barbato and Hafner, 1998;Vieta et al, 2000a;Rossi et al, 2001;Kay et al, 2002;Brieger et al, 2003;George et al, 2003). The personality disorders found to occur most frequently in patients with bipolar disorder, are obsessive-compulsive, borderline, narcissistic and avoidant (Rossi et al, 2001;Brieger et al, 2003).…”

Section: Comorbidity In Bipolar Disordermentioning

confidence: 99%

“…The personality disorders found to occur most frequently in patients with bipolar disorder, are obsessive-compulsive, borderline, narcissistic and avoidant (Rossi et al, 2001;Brieger et al, 2003). Although comorbid personality disorders in bipolar disorder are well recognized by clinicians, there are few studies that have carefully chronicled the impact of personality disturbance on treatment outcomes (Dunayevich et al, 2000;Frankenburg and Zanarini, 2002).…”

Section: Comorbidity In Bipolar Disordermentioning

confidence: 99%

Comorbidity in bipolar disorder: a framework for rational treatment selection

McIntyre

Konarski

Yatham

2004

Human Psychopharmacology

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Bipolar disorders are heterogeneous disorders often requiring multimodality treatment. The expanding pharmacopeia for bipolar disorders invites the need for a treatment framework that both recognizes and anticipates the multidimensionality and comorbidity of the illness. No available neurotherapeutic agent is singularly efficacious for the complete mélange of bipolar symptomatology. An apparent paradox has emerged in the management of bipolar disorder; whilst results from rigorous controlled monotherapy trials suggest that a disparate assortment of neurotherapeutic agents are efficacious in distinct phases of bipolar disorder, the majority of tertiary-treated bipolar patients receive polypharmacotherapeutic regimens. The evidentiary base for polypharmacotherapy is sparse and has recently become an area of active research focus. In the interim, clinicians are encouraged to invoke an organizational schema for the treatment of bipolar disorder that considers the spectrum of effectiveness of putative and established mood stabilizers. This schema should be further informed by the treatment data for comorbid and accessory conditions. The authors propose a schema to provide the impetus for further work in the area.

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Personality disorders in bipolar and depressive disorders

Cited by 74 publications

References 22 publications

Personality disorders in euthymic bipolar patients: a systematic review

Personality disorders in euthymic bipolar patients: a systematic review

Obsessive-compulsive (anankastic) personality disorder: toward the ICD-11 classification

Comorbidity in bipolar disorder: a framework for rational treatment selection

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