Personality, Brain Asymmetry, and Neuroendocrine Reactivity in Two Immune-Mediated Disorders: A Preliminary Report

Martins, João Martin; Alves, João Ferreira; Trinca, A; Grima, Bruno; Vale, Sónia do; Vasconcelos, Teresa; Riso, Nuno; Riscado, Vaz; Costa, José Charneco da

doi:10.1006/brbi.2001.0636

Cited by 18 publications

(14 citation statements)

References 68 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…There are clinical observations that indicate that adrenal tumors causing primary aldosteronism are 2 or 3 times more likely to occur on the left than on the right side [36]. Furthermore, several data indicate associations between cerebral dominance, the reactivity of the hypothalamo-pituitary-adrenal axis and the pathogenesis of certain immune-mediated diseases [37].…”

Section: Functional Considerationsmentioning

confidence: 99%

Recent findings on the organization of central nervous system structures involved in the innervation of endocrine glands and other organs; observations obtained by the transneuronal viral double-labeling technique

Gerendai

Tóth

Boldogkői

et al. 2009

Endocr

View full text Add to dashboard Cite

This review summarizes the data obtained with the aid of the recently introduced dual viral tracing technique, which uses isogenic recombinants of pseudorabies virus that express unique reporter gene. This approach made possible to explore simultaneously neural circuits of two organs. The results of these studies indicate: (1) there are neurons innervating exclusively a given organ; (2) left-sided predominance in the supraspinal innervation of the endocrine glands (adrenal, ovary) studied, so far; (3) viral co-infection of neurons, i.e., special neuronal populations coexist in different brain areas that are transsynaptically connected with both paired endocrine and non-endocrine organs, endocrine glands and non-endocrine organs, and organs of bodily systems other than the endocrine one. The number of common neurons seems to be related to the need of coordinating action of different systems. The data on co-infection of neurons suggest that the central nervous system has the capacity to coordinate different organ functions via common brain neurons providing supraspinal innervation of the organs.

show abstract

Section: Functional Considerationsmentioning

confidence: 99%

Recent findings on the organization of central nervous system structures involved in the innervation of endocrine glands and other organs; observations obtained by the transneuronal viral double-labeling technique

Gerendai

Tóth

Boldogkői

et al. 2009

Endocr

View full text Add to dashboard Cite

show abstract

“…However, the autopsy data, which indicate that in suicide victims the left, but not the right gland is significantly heavier than in sudden death, nonpsychiatric controls (Szigethy et al, 1994) might suggest that the asymmetry in the supraspinal innervation could play a significant role in the control of the organ. Furthermore, increasing number of data indicate associations between cerebral asymmetry, hypothalamo-pituitary-adrenal reactivity, and pathogenesis of certain immune-mediated diseases (Martins et al, 2002).…”

Section: Asymmetry Of the Innervationmentioning

confidence: 99%

Transneuronal retrograde viral labeling in the brain stem and hypothalamus is more intense from the left than from the right adrenal gland

Tóth

Wiesel

Tóth

et al. 2008

Microscopy Res & Technique

View full text Add to dashboard Cite

Previous studies using the viral transneuronal tracing technique demonstrated central autonomic circuits involved in the innervation of the adrenal gland. Since increasing number of data indicate laterality in the neuroendocrine system, we aimed to investigate whether the supraspinal innervation of the adrenal gland exhibits asymmetry or not. The central circuitry involved in the innervation of the left and the right adrenal gland was studied in individual rats by dual transneuronal tracing using isogenic recombinant strains (Ba-DupGreen and Ba-Duplac expressing lacZ) of Bartha strain of pseudorabies virus. Viral infection of brain nuclei (dorsal vagal nucleus, nucleus of the solitary tract, caudal raphe nuclei, A5 cell group, hypothalamic paraventricular nucleus) from the left adrenal was more severe than that from the right organ. Dual-infected neurons were present both in the brain stem and in the hypothalamus. The results indicate a predominance in the supraspinal innervation of the left adrenal gland, and that each adrenal gland is innervated both by side-specific neurons and by neurons that project to both organs.

show abstract

“…Some studies have considered some psychological variables in SLE patients, namely: personality dimensions [4] , life events [5] , lower self-esteem, and social support [6] . From our literature review, references to alexithymia in SLE patients were scarce.…”

mentioning

confidence: 99%

Alexithymia and Clinical Variables in SLE Patients

Barbosa

Mota²,

Patrício

et al. 2011

Psychother Psychosom

View full text Add to dashboard Cite

Personality, Brain Asymmetry, and Neuroendocrine Reactivity in Two Immune-Mediated Disorders: A Preliminary Report

Cited by 18 publications

References 68 publications

Recent findings on the organization of central nervous system structures involved in the innervation of endocrine glands and other organs; observations obtained by the transneuronal viral double-labeling technique

Recent findings on the organization of central nervous system structures involved in the innervation of endocrine glands and other organs; observations obtained by the transneuronal viral double-labeling technique

Transneuronal retrograde viral labeling in the brain stem and hypothalamus is more intense from the left than from the right adrenal gland

Alexithymia and Clinical Variables in SLE Patients

Contact Info

Product

Resources

About