Abstract:This article describes the development of a mathematical model for evaluation of particle concentration for indoor air conditions. The results of modeling could be used to predict particle concentration in an ambient air at different distances from the source, taking into account space geometry and ventilation/air conditioning created air streams. Two case studies were then undertaken to determine the particle concentration at hypothetical shopping center for the situations when: (1) the ambient air movement i… Show more
“…The parameter N is the previously mentioned threshold with an average value of 4. As shown in Fig.1B, when the virus concentration in the body exceeds 4×10 4 units/m 3 [6], the rate of virus reproduction will be greatly increased.…”
In this paper, we construct a stochastic model of the 2019-nCoV transmission in a confined space, which gives a detailed account of the interaction between the spreading virus and mobile individuals. Different aspects of the interaction at mesoscopic level, such as the human motion, the shedding and spreading of the virus, its contamination and invasion of the human body and the response of the human immune system, are touched upon in the model, thier relative importance during the course of infection being evaluated. The model provides a bridge linking the epidemic statistics to the physiological parameters of individuals and may serve a theoretical guidance for epidemic prevention and control.
“…The parameter N is the previously mentioned threshold with an average value of 4. As shown in Fig.1B, when the virus concentration in the body exceeds 4×10 4 units/m 3 [6], the rate of virus reproduction will be greatly increased.…”
In this paper, we construct a stochastic model of the 2019-nCoV transmission in a confined space, which gives a detailed account of the interaction between the spreading virus and mobile individuals. Different aspects of the interaction at mesoscopic level, such as the human motion, the shedding and spreading of the virus, its contamination and invasion of the human body and the response of the human immune system, are touched upon in the model, thier relative importance during the course of infection being evaluated. The model provides a bridge linking the epidemic statistics to the physiological parameters of individuals and may serve a theoretical guidance for epidemic prevention and control.
“…As shown in Fig. 1 , when the virus concentration in the body exceeds units/m [ 15 ], the rate of virus reproduction will be greatly increased. Fig.…”
In this paper, we construct a stochastic model of the 2019-nCoV transmission in a confined space, which gives a detailed account of the interaction between the spreading virus and mobile individuals. Different aspects of the interaction at mesoscopic level, such as the human motion, the shedding and spreading of the virus, its contamination and invasion of the human body and the response of the human immune system, are touched upon in the model, their relative importance during the course of infection being evaluated. The model provides a bridge linking the epidemic statistics to the physiological parameters of individuals and may serve a theoretical guidance for epidemic prevention and control.
“…The most recent results were obtained by mathematical evaluation of the possibility of using the new technique for outdoor [39] and indoor [40] sampling procedures. It was found and theoretically justified that, for some realistic concentration of biological particles at a source, the new technique would be able to obtain the reliable results, even at distances of up to 800 m downstream.…”
Section: Performance Charcteristics Of the Devicementioning
A new personal bioaerosol sampler has been developed and verified as an efficient tool for monitoring of viable/non-viable airborne microorganisms, including bacteria, fungi, and viruses. The operational principle of the device is based on continuous passage of an air sample through porous media submerged into a liquid layer. During motion along narrow and tortuous ways inside the porous media, the air stream is split into a large number of ultra small bubbles with the particulates are being scavenged by these bubbles and, thus, effectively trapped. The device was initially verified for monitoring of viable airborne bacteria and fungi, firstly, under controlled laboratory conditions and later in a field. It was demonstrated that bacterial recovery rates for these two groups of microorganisms were very high and the device was found to be fully feasible for such monitoring. The next step of the device investigation was performed in the laboratory on monitoring viable airborne viruses with a range of sensitivities to physical and biological stresses. As the result, the new personal sampler demonstrated a very high recovery rate even for viruses which are rather sensitive to environmental stress (Avian Influenza, SARS, Mumps, etc.). Some following field studies, undertook in a hospital and animal houses, also demonstrated an excellent performance of the new device for selective and reliable monitoring of viable airborne viruses even in environments highly contaminated by other microorganisms. This paper reviews the main development staged of the new personal bioaerosol sampler.
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