Persistent Primitive Olfactory Artery in Serbian Population

Abstract

The continuation of the cranial branch of the primitive internal carotid artery is called the primitive olfactory artery (POℓA). It takes this name according to the fact that it is mainly concerned with supplying the developing nasal region. We reported two new cases of the persistent POℓA (PPOℓA) in Serbian population after retrospective analysis of digital images of 200 fetal and 269 adult cases. This PPOℓA originated from the precommunicating part (A1) of the right anterior cerebral artery, coursed along the olfactory tract, and turned on the medial cerebral hemisphere in both male adults. Some vascular variations (fenestration of the A1 and the median artery of the corpus callosum) were associated with this persistent vessel. According to the fact that we did not find aneurysm in our previous and two recent cases, we are of the opinion that PPOℓA is usually asymptomatic in Serbian population.

Persistent Fetal Intracranial Arteries

“…The variation is more frequent in males and on the left side (Vasovic et al 2013). Only five bilateral cases have been reported (Vasovic et al 2013). The incidences of the persistent primitive olfactory artery are given as 0.64% in the Serbian and 0.14% in the Japanese populations (Uchino et al 2011), and 0.29% in the Korean population (Vasovic et al 2013).…”

“…A persistent primitive olfactory artery, which is highly associated with cerebral aneurysms, is very rare (Nozaki et al 1998;Vasovic et al 2013). It represents a continuation of the cranial branch of the primitive internal carotid artery (Vasovic et al 2013).…”

“…It represents a continuation of the cranial branch of the primitive internal carotid artery (Vasovic et al 2013). It arises from the terminal portion of the internal carotid and courses anteromedially along the ipsilateral olfactory tract and makes a hair-pin curve posterior to the olfactory bulb (Padget 1948), becoming the distal anterior cerebral artery (variant 1) or the ethmoidal artery (variant 2).…”

“…It arises from the terminal portion of the internal carotid and courses anteromedially along the ipsilateral olfactory tract and makes a hair-pin curve posterior to the olfactory bulb (Padget 1948), becoming the distal anterior cerebral artery (variant 1) or the ethmoidal artery (variant 2). It is suggested that a relatively frequent location of an aneurysm on the hairpin bend of the persistent primitive olfactory emphasizes the importance of hemodynamic stress in this vessel (Nozaki et al 1998;Yamamoto et al 2009;Vasovic et al 2013).…”

“…According to Vasovic et al (2013), 67 cases had been reported in the literature up to that time. The variation is more frequent in males and on the left side (Vasovic et al 2013). Only five bilateral cases have been reported (Vasovic et al 2013).…”